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| Catalog Number | CI-BP-0157 |
| Product Name | Tripeptide-32 |
| Purity | 0.95 |
| Appearance | White powder |
| Storage | -15~-20 °C |
| Safety | No heavy metals, no skin and eye irritation |
Tripeptide-32, known commercially as Chronolux®, is a synthetic peptide that plays a pivotal role in enhancing the skin's natural repair mechanisms by aligning with the body's circadian rhythms. Its primary function involves the activation of specific genes, namely CLOCK (Circadian Locomotor Output Cycles Kaput) and PER1 (Period Homolog 1), within keratinocytes. By stimulating the CLOCK gene, Tripeptide-32 initiates the production of various proteins and enzymes essential for DNA repair, thereby enhancing cell viability and longevity while protecting against environmental stressors such as UV exposure and pollution. Furthermore, the activation of the PER1 gene by Tripeptide-32 aids in DNA repair processes synchronized with the day/night cycle, substantially improving keratinocyte survival. This action helps maintain the skin's natural beauty and barrier function, effectively countering premature aging and supporting a healthy complexion.
What is Tripeptide-32 and how does it work?
Tripeptide-32 is a synthetic peptide with the sequence Ser-Thr-Pro-NH2. It functions by activating specific genes such as CLOCK (Circadian Locomotor Output Cycles Kaput) and PER1 (Period Homolog 1) in keratinocytes. These genes play a crucial role in regulating cellular defense mechanisms in alignment with circadian rhythms, which are the body's 24-hour cycles. By stimulating these genes, Tripeptide-32 promotes DNA repair, enhances cell viability and longevity, and strengthens the skin's defenses against environmental factors like UV exposure, pollution, and cigarette smoke.
How does Tripeptide-32 contribute to skin protection during daylight hours?
Tripeptide-32 contributes to skin protection by regulating the activation of genes associated with the body's natural defense systems, which are most active during daylight. By activating the CLOCK gene in keratinocytes, Tripeptide-32 initiates a cascade that produces various proteins and enzymes responsible for repairing damaged DNA. This process helps improve cell viability and longevity, providing defense against harmful environmental factors typically encountered during the day.
What are the benefits of activating the PER1 gene with Tripeptide-32?
By activating the PER1 gene, Tripeptide-32 enhances DNA repair processes that follow the day/night cycle, effectively improving keratinocyte survival rates. This activation helps preserve the skin's natural beauty and barrier function, guarding against premature aging and maintaining overall skin health.
Can Tripeptide-32 prevent premature aging of the skin?
Yes, Tripeptide-32 can help prevent premature aging of the skin. By activating genes involved in circadian rhythm regulation and DNA repair, it improves the skin's natural ability to repair and defend itself against environmental stressors. This results in enhanced skin resilience and longevity, reducing the visible signs of aging and helping to maintain a youthful appearance.
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