Anti-wrinkle Peptides

Anti-wrinkle Peptides

Wrinkles are visible creases or folds in the skin, and they are usually the first sign of aging. Changes in appearance caused by wrinkles can have a negative impact on quality of life. In some cases, concerns about appearance can affect interpersonal interactions, occupational functioning, and self-esteem.

Anti-wrinkle peptides are small proteins that can penetrate the skin to moisturize it and help smoothen fine lines and wrinkles.

Beauty Peptides

Anti-wrinkle Mechanisms

The dermal-epidermal junction (DEJ) not only separates the epidermis from the dermis of the skin, but also provides a biochemical interface between the epidermis and the dermis. In intrinsically aged skin, thinning and flattening of the DEJ structure is commonly observed, which results in impaired adhesion of the epidermis to the dermis, leading to reduced mechanical stability and structural integrity.

Based on the important role of the DEJ in skin homeostasis, modulation of basement membrane proteins has been recognized as one of the potential strategies to ameliorate skin wrinkles. Specially, some anti-wrinkle peptides may act as major components of anchoring protofibrils that provide mechanical support to keratinocytes, and they play an important role in the assembly and function of cell-matrix adhesion structures and are important in transmembrane signaling and keratinocyte differentiation. In addition, they can participate in skin re-epithelialization and wound healing by regulating the activities of core cells such as adhesion, proliferation, migration, apoptosis, and differentiation.

As a leading provider of cosmetic raw materials, Alfa Chemistry can supply high-quality beauty peptides to cosmetic companies looking to create innovative skincare products. Contact us today to learn more about how we can help you achieve your skincare goals.

References

1. Jeong S, Yoon S, Kim S, Jung J, Kor M, Shin K, Lim C, Han HS, Lee H, Park KY, Kim J, Chung HJ, Kim HJ. Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression. Int J Mol Sci. 2019 Dec 20;21(1):73.
2. Khalid KA, Nawi AFM, Zulkifli N, Barkat MA, Hadi H. Aging and Wound Healing of the Skin: A Review of Clinical and Pathophysiological Hallmarks. Life (Basel). 2022 Dec 19;12(12):2142.

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Anti-wrinkle Peptides

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