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| Catalog Number | CI-BP-0113 |
| Product Name | Tetrapeptide-26 |
| Purity | 0.95 |
| Appearance | White powder |
| Storage | -15~-20 °C |
| Safety | No heavy metals, no skin and eye irritation |
Tetrapeptide-26, under the trade name Chronogen®, is a synthetic peptide that plays a crucial role in enhancing the skin's defense mechanisms through its interaction with the circadian rhythm. By activating key genes such as CLOCK, BMAL1, and PER1 in keratinocytes, Tetrapeptide-26 facilitates the regulation of proteins responsible for cellular defense processes. This peptide works to bolster the skin's natural defenses against environmental damage like UV exposure during the day and supports DNA repair processes at night. Distinguished from similar compounds like Tripeptide-32, Tetrapeptide-26 notably enhances the expression of BMAL1, forming an effective heterodimer complex with CLOCK and thereby optimizing the skin's defense proficiency. This innovation allows the skin's defensive activities to occur independently of the day/night cycle, ultimately improving keratinocyte survival rates after exposure to harmful environmental factors. This aspect is particularly beneficial for individuals residing in urban settings. Moreover, Tetrapeptide-26 strengthens the skin barrier, supports overall skin health, and aids in the prevention of premature aging, offering a simplified and effective addition to skincare routines.
What is Tetrapeptide-26 and how does it work?
Tetrapeptide-26 is a synthetic peptide with the sequence Ser-Pro-Leu-Gln-NH2. It functions by activating specific genes in the skin's keratinocytes, such as CLOCK, BMAL1, and PER1, which are vital for regulating cellular defense mechanisms linked to the skin's circadian rhythm. This activation helps enhance the skin's natural defenses against environmental damage during the day and increases DNA repair processes at night.
How does Tetrapeptide-26 compare to other peptides like Tripeptide-32?
Tetrapeptide-26 and Tripeptide-32 both promote natural defenses against UV radiation and environmental damage at a cellular level. However, Tetrapeptide-26 uniquely enhances the expression of the BMAL1 gene, improving the peptide's overall effectiveness by forming a heterodimer complex with CLOCK. This enhancement boosts the production of proteins involved in DNA repair processes, providing superior skin protection and repair capabilities.
What benefits can I expect from using Tetrapeptide-26 in my skincare routine?
By boosting the production of proteins involved in DNA repair and enhancing skin's natural defense mechanisms, Tetrapeptide-26 significantly improves keratinocyte survival rates when exposed to environmental damage. It strengthens the skin barrier, preserves skin health, and prevents premature aging. This makes it particularly advantageous for those living in urban areas subject to high levels of environmental stressors.
Can Tetrapeptide-26 be used both during the day and at night?
Yes, Tetrapeptide-26 is formulated to work independently of the skin's natural day/night cycle, making it suitable for use both during the day and at night. This simplifies customers' skincare routines while ensuring continuous protection and repair functions, helping maintain healthy skin 24/7.
Who would benefit most from using Tetrapeptide-26?
Tetrapeptide-26 is particularly beneficial for individuals who are frequently exposed to environmental stressors such as UV radiation and pollution, which is common in urban areas. Anyone looking to strengthen their skin barrier, preserve skin health, and prevent premature aging can benefit from incorporating Tetrapeptide-26 into their skincare regimen.
If you have any questions, please contact us. You will get a satisfactory answer.
