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| Catalog Number | CI-FC-0032 |
| Product Name | Sodium carboxymethyl beta-glucan |
| CAS | 9050-93-5 |
| Synonyms | Carboxymethylglucan |
Sodium carboxymethyl beta-glucan is a water-soluble derivative of beta-glucan, specifically modified as an effective ingredient for cosmetic and dermatological use. Building on the historical application of yeast-derived extracts in various pharmaceutical and cosmetic products, Sodium carboxymethyl beta-glucan offers advanced benefits due to its significant role as a biological response modifier. This compound is derived from the beta-glucan found in yeast cell walls, which has been identified over recent years as a key immunologically active component. Known for its ability to enhance nonspecific defense mechanisms, Sodium carboxymethyl beta-glucan has been the subject of extensive research, particularly in areas such as wound healing, oncology, and dermatology. Its inclusion in formulations provides antioxidant properties, cell growth promotion, and protection, making it a valuable addition to a range of topical applications.
What are the primary cosmetic benefits of Sodium Carboxymethyl Beta-Glucan?
Sodium Carboxymethyl Beta-Glucan, also known as CM-Glucan, offers several cosmetic benefits. It is particularly effective in protecting skin cells from the depletion of antioxidant molecules following exposure to UV-A radiation. It also provides considerable protection against skin damage caused by detergents and promotes the growth of keratinocytes, thereby enhancing the renewal rate of the stratum corneum. Additionally, it protects skin lipids from oxidation induced by UV-A radiation.
How effective is Sodium Carboxymethyl Beta-Glucan at low concentrations?
CM-Glucan is highly functional even at low concentrations, displaying its multifaceted protective and enhancing properties at concentrations as low as 0.01-0.04%. This makes it an efficient ingredient in various cosmetic formulations.
What results have studies shown regarding the use of Sodium Carboxymethyl Beta-Glucan against UV-A radiation?
In a clinical study involving 10 volunteers, the skin was pretreated with CM-Glucan for five days before being exposed to UV-A radiation. The skin's response, specifically the level of lipid peroxides, was monitored, and it was observed that the application of a 0.2% CM-Glucan oil-in-water emulsion provided 95% protection against lipid oxidation. This level of protection could not be matched by even the best antioxidants, demonstrating the potent ability of CM-Glucan to safeguard the skin.
Can Sodium Carboxymethyl Beta-Glucan be considered effective in anti-aging skin care?
Given its ability to promote keratinocyte growth, improve the renewal rate of the stratum corneum, and protect skin lipids from oxidative stress, CM-Glucan can be considered a valuable ingredient in anti-aging formulations. These properties contribute to healthier, more resilient skin, which is crucial in countering the effects of aging.
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