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Pal-tetrapeptide-3/7

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Catalog Number	CI-BP-0004
Product Name	Pal-tetrapeptide-3/7
CAS	221227-05-0
Structure
Synonyms	Palmitoyl tetrapeptide-7
IUPAC Name	(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[2-(hexadecanoylamino)acetyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Molecular Weight	694.91 g/mol
Molecular Formula	C34H62N8O7
InChI	InChI=1S/C34H62N8O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-19-29(44)39-24-30(45)40-25(20-21-28(35)43)32(47)42-23-16-18-27(42)31(46)41-26(33(48)49)17-15-22-38-34(36)37/h25-27H,2-24H2,1H3,(H2,35,43)(H,39,44)(H,40,45)(H,41,46)(H,48,49)(H4,36,37,38)/t25-,26-,27-/m0/s1
InChI Key	IHRKJQSLKLYWBQ-QKDODKLFSA-N
Purity	0.95
Density	1.26 g/mL
Appearance	Solid
Isomeric SMILES	CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O
pKa	3.60±0.21

Product Overview

Pal-tetrapeptide-3/7, also known as Palmitoyl Tetrapeptide-7, serves as a sophisticated skincare solution aimed at mimicking the activity of DHEA, thereby contributing to the restoration of cytokine equilibrium in aging skin. As a lipopeptide developed by Sederma, it encompasses the sequence Pal-GQPR, derived from immunoglobulin G, often dubbed the "youth hormone molecule." With aging, natural levels of DHEA diminish, leading to an increase in interleukin-6. By addressing this imbalance, Pal-tetrapeptide-3/7 aids in enhancing youthful skin appearance by managing both basal and UV-induced interleukin-6 secretions in keratinocytes and fibroblasts, functioning similarly to DHEA.

Custom Q&A

What is Palmitoyl Tetrapeptide-7, and how does it benefit the skin?

Palmitoyl Tetrapeptide-7 is a peptide compound used in skincare products to help maintain the skin's youthful appearance. It works by reducing the production of Interleukin-6 (IL-6) in critical skin cells such as keratinocytes and fibroblasts. IL-6 is a significant inflammatory mediator that can cause quicker degradation of extracellular matrix components, leading to the formation of wrinkles and decreased skin firmness and elasticity. By lowering IL-6 and other pro-inflammatory agents, Palmitoyl Tetrapeptide-7 helps protect these extracellular components from degradation, thus preserving the skin's natural youthfulness and supporting its replenishment.

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