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| Catalog Number | CI-BP-0065 |
| Product Name | Palmitoyl dipeptide-10 |
| CAS | 324755-72-8 |
| Synonyms | N-(1-Oxohexadecyl)-beta-alanyl-L-histidine |
| IUPAC Name | (2S)-2-[3-(hexadecanoylamino)propanoylamino]-3-(1H-imidazol-5-yl)propanoic acid |
| Molecular Weight | 464.64 g/mol |
| Molecular Formula | C25H44N4O4 |
| InChI | InChI=1S/C25H44N4O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-23(30)27-17-16-24(31)29-22(25(32)33)18-21-19-26-20-28-21/h19-20,22H,2-18H2,1H3,(H,26,28)(H,27,30)(H,29,31)(H,32,33)/t22-/m0/s1 |
| InChI Key | LNXLHAWHHNDIDC-QFIPXVFZSA-N |
| Isomeric SMILES | CCCCCCCCCCCCCCCC(=O)NCCC(=O)N[C@@H](CC1=CN=CN1)C(=O)O |
| Safety | No heavy metals, no skin and eye irritation |
Palmitoyl Dipeptide-10, also known as SunPEP Di-100 and C-Pep™, is a synthetic lipopeptide with a sequence of Pal-Ala-His, designed to mimic the action of Carnosine while offering unique benefits. It is distinguished by its notable antioxidant properties that effectively neutralize free radicals and guard cells against oxidative damage. By preventing the glycation and crosslinking of structural proteins in the skin, Palmitoyl Dipeptide-10 delivers significant anti-aging effects. The palmitoylation of Dipeptide-10 enhances its ability to penetrate the skin, increases its stability within formulations, and provides protection against degradation by proteolytic enzymes. Moreover, this peptide is claimed to aid in protecting dermal cells from oxidative stress, expedite wound healing, and combat cellular aging. It contributes to increasing the amount of functional extracellular matrix proteins while defending the skin against glycation and reactive carbonyl species.
What is Palmitoyl Dipeptide-10?
Palmitoyl Dipeptide-10 is a synthetic lipopeptide consisting of a sequence known as Pal-Ala-His. It is structurally similar to Carnosine, but chemically distinct. It is known for its potent antioxidant properties, which help in scavenging free radicals and protecting cells from oxidative damage.
How does Palmitoyl Dipeptide-10 benefit the skin?
Palmitoyl Dipeptide-10 provides several skin benefits. It prevents glycation and crosslinking of the skin's structural proteins, contributing to noticeable anti-aging effects. Additionally, its antioxidant properties protect the skin from oxidative stress. The peptide also increases the amount of functional extracellular matrix (ECM) proteins, supports wound healing, and combats cellular senescence.
What is the significance of palmitoylation in Palmitoyl Dipeptide-10?
Palmitoylation, the process of conjugating Dipeptide-10 with Palmitic acid, enhances various properties of the peptide. It improves skin penetration, increases peptide stability within formulations, and protects it from degradation by proteolytic enzymes. This modification ensures that the peptide maintains its efficacy and offers prolonged benefits when applied to the skin.
How does Palmitoyl Dipeptide-10 compare with Carnosine?
While both Palmitoyl Dipeptide-10 and Carnosine have similar antioxidant capabilities due to their structural resemblance, they are different chemically. Palmitoyl Dipeptide-10 has enhanced stability and skin penetration due to its palmitoylation, which Carnosine does not possess, leading to distinct advantages in dermatological applications such as improved efficacy in topical skincare products.
Can Palmitoyl Dipeptide-10 aid in wound healing?
Yes, according to the manufacturer's claims, Palmitoyl Dipeptide-10 can accelerate the healing of wounds. Its ability to protect dermal cells from oxidative damage and its role in increasing the amount of functional ECM proteins facilitate faster recovery and repair of damaged skin tissues.
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