Our customer service representatives are available 24 hours a day, from Monday to Sunday.
| Catalog Number | CI-BP-0147 |
| Product Name | Oligopeptide-10 |
| CAS | 466691-40-7 |
| Synonyms | L-Leucinamide, L-phenylalanyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-lysyl-L-alanyl- |
| Molecular Weight | 1598.07 g/mol |
| Molecular Formula | C78H140N20O15 |
| Boiling Point | 1733.4±65.0 °C |
| Purity | 0.95 |
| Density | 1.151 g/mL |
| Appearance | White powder |
| Storage | -15~-20 °C |
| pKa | 13.42±0.46 |
| Safety | No heavy metals, no skin and eye irritation |
Oligopeptide-10, a peptide consisting of 15 amino acids, is widely used in contemporary anti-acne treatments due to its broad-spectrum antibacterial properties, particularly against Gram-positive bacteria such as Cutibacterium acnes. It functions by targeting the cytoplasmic membranes of bacteria to induce osmotic imbalance, effectively leading to bacterial cell death. This mechanical action means that bacteria cannot easily develop resistance to Oligopeptide-10, setting it apart from traditional antibiotics. As a water-soluble white powder, it is compatible with various emulsion types within a pH range of 5-7 and can be seamlessly incorporated into skincare formulations. By eliminating harmful bacteria, it helps reduce skin redness and irritation, promoting a clearer and more even skin tone. Known for its safety, Oligopeptide-10 presents a low irritation and sensitization profile, is non-toxic, and demonstrates non-mutagenic properties. Furthermore, it enhances the skin's natural defense mechanisms. Oligopeptide-10 is often used in conjunction with salicylic acid and other anti-acne agents, working synergistically to deliver optimal results. Clinical studies have shown that formulations containing this peptide significantly reduce acne-related redness and blemishes.
What is Oligopeptide-10 and how does it work?
Oligopeptide-10 is a 15-amino-acid-long peptide designed specifically for skincare applications. It is known for its broad-spectrum antibacterial properties, particularly effective against Gram-positive bacteria like Cutibacterium acnes. The mechanism involves binding to negatively charged lipoteichoic acids on bacterial membranes, targeting the cytoplasmic membranes, and inducing osmotic imbalances, leading to bacterial cell death. This mechanical action prevents bacteria from developing resistance, unlike traditional antibiotics.
In what skincare applications is Oligopeptide-10 most commonly used?
Oligopeptide-10 is primarily used in anti-acne skincare formulations. Its antibacterial properties make it effective in reducing acne-related symptoms such as redness, irritation, and blemishes. It is often combined with other anti-acne ingredients like salicylic acid for synergistic effects, enhancing the overall efficacy of the skincare treatment.
Is Oligopeptide-10 safe to use on sensitive skin?
Yes, Oligopeptide-10 is considered safe for use on sensitive skin. It is non-toxic and has a low irritation and sensitization profile. Additionally, it is non-mutagenic, making it suitable for a wide range of skincare products without causing harm or adverse reactions.
Can bacteria develop resistance to Oligopeptide-10?
No, bacteria cannot develop resistance to Oligopeptide-10 in the manner they do with traditional antibiotics. This is because Oligopeptide-10's mechanism of action is mechanical rather than enzymatic, targeting the bacterial membrane directly, which prevents the development of resistance.
How does Oligopeptide-10 improve skin appearance?
By effectively eliminating harmful bacteria, Oligopeptide-10 reduces skin redness and irritation, promoting a healthy, radiant, and uniform skin appearance. Additionally, it enhances the skin's natural defense mechanisms, leading to improved overall skin health and resilience.
What are the formulation considerations for including Oligopeptide-10 in skincare products?
Oligopeptide-10 is a water-soluble white powder compatible with all emulsion types in the pH range of 5-7. This makes it suitable for various formulations. Its compatibility with other anti-acne ingredients such as salicylic acid allows for the development of potent synergistic skincare solutions.
If you have any questions, please contact us. You will get a satisfactory answer.
