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| Catalog Number | CI-BP-0117 |
| Product Name | Octapeptide-11 |
| Purity | 0.95 |
| Solubility | Soluble in water |
| Appearance | White powder |
| Storage | -15~-20 °C |
| Safety | No heavy metals, no skin and eye irritation |
Octapeptide-11, also known as CG-Seperin, is a synthetic peptide comprising the sequence Met-Ile-Pro-Cys-Tyr-Ile-Ser-Ser. It functions primarily as an inhibitor of the Matrix Metalloproteinase (MMP) enzyme, which is implicated in the degradation of hyaluronic acid. By inhibiting MMP, Octapeptide-11 preserves hyaluronic acid in its high-molecular-weight form, thereby enhancing the skin's capacity for water retention and improving smoothness and elasticity. Additionally, it reduces the levels of low-molecular-weight hyaluronic acid, which can contribute to the production of pro-inflammatory cytokines, thus offering an anti-inflammatory and soothing benefit to the skin. By hindering collagen degradation, Octapeptide-11 aids in sustaining the skin's firmness and suppleness, promoting a smoother, more youthful, and radiant appearance. It also plays a critical role in protecting dermal cells from apoptosis due to oxidative stress.
What is Octapeptide-11, and how does it benefit the skin?
Octapeptide-11 is a synthetic peptide with the sequence Met-Ile-Pro-Cys-Tyr-Ile-Ser-Ser, commercially known as CG-Seperin. It benefits the skin by inhibiting the MMP (Matrix MetalloProteinase) enzyme responsible for the degradation of hyaluronic acid. This action helps maintain the hyaluronic acid in a highly polymerized state, enhancing the skin's ability to retain moisture, improving smoothness, elasticity, and contributing to a youthful, radiant appearance.
How does Octapeptide-11 contribute to skin's water retention and elasticity?
By inhibiting MMP activity, Octapeptide-11 prevents the breakdown of hyaluronic acid, which is crucial for skin hydration. It helps retain this acid in a high-molecular-weight state, significantly enhancing the skin's water retention capability and ensuring improved elasticity, smoothness, and overall skin health.
Does Octapeptide-11 have any anti-inflammatory properties?
Yes, Octapeptide-11 has mediated anti-inflammatory and soothing effects on the skin. By reducing the quantities of low-molecular-weight hyaluronic acid (LMWHA), which can stimulate the production of pro-inflammatory cytokines, Octapeptide-11 helps to calm the skin and reduce inflammation.
Can Octapeptide-11 help prevent signs of aging?
Octapeptide-11 helps in suppressing collagen degradation by Matrix MetalloProteinases (MMPs), which supports the maintenance of skin firmness and suppleness. By protecting dermal cells from apoptosis (programmed cell death) due to oxidative stress, it assists in delaying the visible signs of aging, resulting in smoother and more youthful-looking skin.
Are there any protective benefits of using products with Octapeptide-11?
Octapeptide-11 preserves dermal cells from apoptosis following oxidative stress, ensuring that the skin maintains its health and resilience against environmental stressors. This protective quality helps in keeping the skin firm and decreasing the likelihood of premature aging and damage.
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