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| Catalog Number | CI-GU-0030 |
| Product Name | Methylparaben |
| CAS | 99-76-3 |
| Structure |  |
| Synonyms | Methyl Paraben, Methyl Parahydroxybenzoate, Methyl p-hydroxybenzoate |
| IUPAC Name | methyl 4-hydroxybenzoate |
| Molecular Weight | 152.15 g/mol |
| Molecular Formula | C8H8O3 |
| InChI | InChI=1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3 |
| InChI Key | LXCFILQKKLGQFO-UHFFFAOYSA-N |
| Boiling Point | 298.5 °C |
| Melting Point | 125-128 °C |
| Flash Point | 280 °C |
| Purity | 95% |
| Density | 1.46 g/mL |
| Appearance | Solid |
| Isomeric SMILES | COC(=O)C1=CC=C(C=C1)O |
Methylparaben serves as a methyl ester of p-hydroxybenzoic acid and is extensively utilized as a broad-spectrum preservative in personal care products, pharmaceuticals, and some foods. It is both colorless and odorless, ensuring compatibility with a diverse array of cosmetic ingredients. Among organic acid-based preservatives, methylparaben and its paraben counterparts are particularly distinguished for their consistent efficacy across a wide pH range and various conditions. This preservative effectively targets a wide spectrum of microorganisms responsible for the spoilage of cosmetics and pharmaceuticals. Due to its antimicrobial properties, its performance remains reliable even when the pH is not strictly controlled, making it valuable in formulations where pH adjustment errors might occur. When applied at the recommended concentrations, methylparaben demonstrates low toxicity and ecotoxicity. Moreover, it maintains strong antimicrobial activity within the pH range of 4 to 8. When used in conjunction with other parabens, it enhances their preservative effect, allowing formulators to use lower concentrations while achieving the desired antimicrobial protection.
What is Methylparaben used for in personal care products and pharmaceuticals?
Methylparaben is primarily used as a broad-spectrum preservative. It helps protect products from microorganisms responsible for spoilage, ensuring they remain safe and effective for consumers to use over time.
Is Methylparaben compatible with other ingredients in cosmetics?
Yes, Methylparaben is compatible with a wide range of cosmetic ingredients. Because of its neutral characteristics, it can be included in various formulations without altering product consistency or performance.
How effective is Methylparaben as a preservative in different pH levels?
Methylparaben is effective across a broad pH range, from 4 to 8, making it a versatile preservative option. Its antimicrobial properties are stable, even if the product's pH is not adjusted correctly, providing reliable protection against spoilage.
Are there any toxicity concerns associated with Methylparaben?
When used in recommended concentrations, Methylparaben has a low order of toxicity and ecotoxicity. This safety profile makes it an appropriate preservative choice for various applications, ensuring minimal risk to consumers and the environment.
Can Methylparaben be used in combination with other parabens?
Yes, Methylparaben can be combined with other parabens, which usually enhances its antimicrobial activity. This synergy allows formulators to use lower concentrations of preservatives while maintaining efficacy, benefiting both product performance and consumer safety.
What sets Methylparaben apart from other organic acid-based preservatives?
Methylparaben and other parabens are superior due to their stable efficiency across diverse conditions and their broad-spectrum antimicrobial activity. This makes them particularly effective in protecting products without being influenced by changes in product acidity.
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