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| Catalog Number | CI-HC-0142 |
| Product Name | Methyl Diisopropyl Propionamide |
| CAS | 51115-67-4 |
| Structure |  |
| Synonyms | 2-Isopropyl-N,2,3-trimethylbutyramide |
| Description | Methyl Diisopropyl Propionamide (MDPP) is a synthetic compound that belongs to the class of amides. It is often used as a fragrance or odorant in cosmetic and personal care products, as well as in the flavor and perfume industries. Specifically, it is known for providing a fresh, floral and vegetative odour. As an amide, MDPP can also act as a functional ingredient in some formulations, working as a solubilizer, emulsifier or viscosity enhancer. Its solubility in water and various solvents also makes it useful in a range of applications such as perfumes, detergents and pharmaceuticals, among others. |
| IUPAC Name | N,2,3-trimethyl-2-propan-2-ylbutanamide |
| Molecular Weight | 171.28 g/mol |
| Molecular Formula | C10H21NO |
| Canonical SMILES | CC(C)C(C)(C(C)C)C(=O)NC |
| InChI | RWAXQWRDVUOOGG-UHFFFAOYSA-N |
| InChI Key | InChI=1S/C10H21NO/c1-7(2)10(5,8(3)4)9(12)11-6/h7-8H,1-6H3,(H,11,12) |
| Melting Point | 58-61 °C |
| Density | 0.942 g/mL |
| Appearance | colorless to pale yellow liquid with a faint odor |
| Application | 1. Methyl Diisopropyl Propionamide (MDPIPA) is commonly used as a fragrance in cosmetic and personal care products. 2. It can also be used as a flavoring agent in food and beverages. 3. MDPIPA has been reported to have antiviral activity against certain viruses, such as SARS-CoV-2. 4. It has been used as a solvent for various chemical reactions in the pharmaceutical industry. 5. MDPIPA has been reported to have potential as a skin penetration enhancer in topical drug delivery systems. |
| Features And Benefits | 1. Acts as a skin conditioning agent 2. Provides a smooth and silky feel to the skin 3. Enhances the spreadability of the product 4. Helps to improve the absorption of other active ingredients 5. Helps to improve the stability of the formulation |
What is Methyl Diisopropyl Propionamide used for in cosmetics and personal care products?
Methyl Diisopropyl Propionamide (MDPP) serves primarily as a cooling agent in cosmetic and personal care formulations. Renowned for its long-lasting cooling sensation, it offers a refreshing experience similar to menthol, yet with a milder aroma and lower volatility. Additionally, its applications extend to acting as a fragrance, due to its fresh, floral, and vegetative scent, and as a functional ingredient for solubilizing, emulsifying, or enhancing viscosity in various formulations.
Is Methyl Diisopropyl Propionamide safe for all skin types?
Methyl Diisopropyl Propionamide is generally considered safe for use in cosmetics when used as directed. However, individuals with sensitive skin or allergies should perform a patch test before applying products containing this ingredient to larger skin areas to rule out any adverse reactions.
Can Methyl Diisopropyl Propionamide be used in food products?
Yes, Methyl Diisopropyl Propionamide is not only used in cosmetics but also as a flavoring agent in food and beverages, taking advantage of its unique aromatic properties.
How should Methyl Diisopropyl Propionamide be stored?
To maintain its efficacy and stability, Methyl Diisopropyl Propionamide should be stored at room temperature away from heat and light. Proper storage conditions help preserve its quality and extend its shelf life.
Are there any known interactions or stability concerns with Methyl Diisopropyl Propionamide?
Methyl Diisopropyl Propionamide is soluble in water, ethanol, oil, and many glycols, as well as diethyl ether and hydrocarbons, indicating compatibility with a wide range of solvents and formulations. Always ensure that its use in combination with other substances in a product formulation does not lead to undesirable reactions or compromised stability.
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