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Hydrated Silica

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Catalog Number CI-SC-0584
Product Name Hydrated Silica
CAS 10279-57-9 / 1343-98-2 / 7631-86-9 / 112926-00-8 / 63231-67-4
Description Hydrated Silica is a form of silicon dioxide that is used in a number of personal care and cosmetic products. It provides mild abrasion properties that can exfoliate the face properly and aid in the removal of dead skin cells. Hydrated Silica can commonly be found in toothpaste, exfoliating body washes, and facial scrubs. It is also a thickening and viscosity-controlling agent that improves the feel and texture of the products that it is used in. The chemical formula of Hydrated Silica is H10O3Si.
Appearance white, odorless, and tasteless powder
Application 1. Hygiene products - Hydrated silica is commonly used as an abrasive agent in toothpaste, as it helps in removing stains from teeth without damaging the enamel.
2. Skincare - It is used as an ingredient in exfoliating facial cleansers, as it helps in removing dead skin cells and unclogging pores.
3. Food and Beverages - It is used as a food additive in powdered products, such as coffee creamers, to prevent caking and clumping.
4. Pharmaceuticals - It is used as a flow agent in pharmaceutical tablets to ensure consistent drug delivery and prevent sticking to machinery.
5. Coatings and Polishes - Hydrated silica is used in various coatings and polishes to enhance texture, improve scratch resistance, and increase durability.
6. Agriculture - It is used as a carrier for pesticides and fertilizers to help them spread evenly over crops.
Features And Benefits 1. Acts as an abrasive to remove dead skin cells
2. Helps to whiten and brighten teeth
3. Thickens the texture of the product
4. Enhances the transparency of the product
5. Provides slip and glide to the product
6. Absorbs excess oil and sebum
7. Helps to improve the texture and feel of the product on the skin
Case Study

Perfluorodecalin-Encapsulated Silica Nanocapsules for Cosmetic Formulations

Svarc, Federico, et al. Journal Of Dermatological Treatment, 2018, 0954-6634.

Silica and hydrated silica are safe for cosmetic and personal care applications. This work reported the manufacturing of Perfluorodecalin (PFD)-encapsulated silica nanocapsules through a two-step procedure that starts with a stable PFD aqueous nanoemulsion as a template, and precipitates silica "in situ" from sodium silicate as a starting material. In conclusion, silica nanoparticles containing PFD are stable and they could be a novel approach for topical treatment of aging skin.
Synthesis of PFD-encapsulatedsilica nanocapsules
· Mixed in water (77%w/w) at 40-50°C to yield a clear solution of pluronic F127 (2.5%w/w). Then added soy lecithin (0.5% w/w) and PFD (20% w/w) in turns, the latter adding slowly while turning up the temperature to 90°C and vigorously stirring at 3500 rpm.
· The solution's pH spontaneously stabilized at 6-7, then was dialled up to 12 with 0.5 M NaOH. Keeping the temperature at 80-90°C with constant stirring, a 2.0 M Urea solution was added to get a final Urea concentration of 0.5 M, and then a 0.5 M sodium silicate solution was added to get a final concentration of 0.02 M. The sodium silicate caused PFD to slowly precipitate the silica nanoparticles encasing PFD making the system from opaque to milky-white. This took up to three days.
· The precipitate that came out could not be filtered and was centrifuged at 3000 rpm. The precipitate was three times washed in water to remove impurities and dried in an oven at 40°C.

Investigation of the Skin Permeability of Synthetic Amorphous Silica

Bosch, Axel, et al. Toxicology Letters, 2023, Aug 3.

Synthetic amorphous silica (SAS) is considered as a nanomaterial and is therefore subject to general safety discussions. This study used a comprehensive set of analytical techniques (including asymmetric flow field flow fractionation (AF4), inductively coupled plasma mass spectrometry (ICP-MS), scanning electron microscopy combined with energy dispersive X-ray spectroscopy (SEM/EDX)) to investigate the skin penetration potential of SAS.
Cosmetic Formulations and Test Materials
· The aim of the two skin permeation studies (2017 and 2022) was to determine the in vitro percutaneous absorption and mass balance distribution. Each test series used four different forms of SAS in the test system with an experimental period of 24 h.
· The 2017 test series used water-oil emulsions containing 10% hydrated silica, 10% silica, 5% silica dimethyl silicide and 10% silica silicide to evaluate the quantitative risk of 24-hour exposure of porcine skin to formulations containing SAS.
· While the second test series in 2022 used a more complex formulation with nominal test concentrations of 20% hydrated silica, 13% silica, 10% silica dimethyl siloxide and 14% silica siloxide, also containing ethanol, applied to human skin.
Conclusion
· Taking into account the AF4/ICP-MS, SEM-EDX analysis results and relevant literature data as well as the risk assessment performed, it can be concluded that the SAS added to the standard basic cosmetic formulation does not penetrate porcine and human skin and therefore does not raise toxicological concerns.

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