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| Catalog Number | CI-SC-0040 |
| Product Name | Hyaluronic Acid |
| CAS | 9067-32-7 |
| Structure |  |
| Description | Hyaluronic acid is a natural polysaccharide (large sugar molecule) that occurs in various tissues (skin, synovial fluids of joints, connective tissues). Responsible for tissue hydration, lubrication, & tissue stability, holds 500 times its own weight of water. Molecular weight 800-1500kDa. Shelf-life up to 3 years if stored protected from humidity and microbial contamination. |
| Solubility | Water-soluble |
| Appearance | White powder, no odor |
| Application | Hydrating gels, moisturizing creams & lotions, anti-aging & anti-wrinkle products, pre/after sun lotions, protecting / nourishing & moisturizing skin care products, products for sensitive or dry skin. |
| Storage | Store in a closed container at a dry place at room temperature |
| Composition | Sodium hyaluronate |
| Features And Benefits | Most powerful moisturizer and humectant availableProvides smoothness and softening to the skinCan reduce the appearance of wrinklesIdeal ingredient after skin peels |
| GMO | GMO-free |
| HS Code | 3304995000 |
| INCI | Sodium hyaluronate |
| Manufacture | Hyaluronic acid is produced biotechnologically through microbial fermentation with the aid of yeast extract and peptones and serums. |
| Preservation | Preservative-free |
| Purity Grade | No purity grade applicable |
| Raw Material Source | Glucose, soy peptone and yeast extract |
| Uses | Typically used at 0.1-2%. Hyaluronic acid is not readily soluble in water as it binds water very quickly forming a gel. Hyaluronic acid needs to be carefully sprinkled into the water under constant high-speed stirring (preferably with a hand mixer or vortex mixer). The mixture starts then thickening quickly and becomes a gel. At the point no additional hyaluronic acid can be added as there is no water left for hyaluronic acid to be dissolved in (additional hyaluronic acid would only form lumps). |
Hyaluronic acid is a naturally occurring glycosaminoglycan notable for its significant role in maintaining tissue hydration, lubrication, and cellular functions. Found abundantly in youthful skin, synovial fluid, and other human and animal tissues, it is capable of holding substantially more water than any other natural substance-a property that underlies its importance in skin health and joint functionality. Over time, environmental factors such as free radicals, pollution, and UV exposure degrade hyaluronic acid levels in the skin, contributing to aging and the formation of wrinkles. The current advancements in production technologies, exemplified by biosynthetic approaches such as those using Bacillus subtilis, have enabled the development of highly purified hyaluronic acid formulations. This ongoing innovation ensures reduced risks of adverse reactions and enhances the efficacy of hyaluronic acid in both dermatological applications and beyond.
What is Hyaluronic Acid, and how does it benefit the skin and body?
Hyaluronic Acid is a naturally occurring substance found abundantly in the skin, synovial fluid, and other tissues in both humans and animals. It plays a crucial role in tissue hydration, lubrication, and cellular function. Its ability to retain moisture allows it to hold 70% more water than any other natural substance. This makes Hyaluronic Acid essential for maintaining youthful, hydrated skin. Over time, factors such as free radicals, pollution, and UV exposure can degrade Hyaluronic Acid in the skin, leading to dryness and wrinkles. Regular application can help replenish this vital component, promoting smoother and more hydrated skin.
What is the difference between Hyaluronic Acid and Sodium Hyaluronate?
Sodium Hyaluronate is the sodium salt form of Hyaluronic Acid. Both compounds have similar hydrating properties, but Sodium Hyaluronate has a smaller molecular size, which allows it to penetrate the skin more effectively. This makes it an excellent choice for topical skincare products aimed at hydrating the deeper layers of the skin.
How is modern Hyaluronic Acid produced?
Modern Hyaluronic Acid is produced through a biosynthetic process using a novel strain of Bacillus subtilis. This non-animal-derived method replaces the older, ethically questionable extraction from rooster combs. This patented fermentation process ensures a high purity level while avoiding organic solvents during recovery, significantly reducing the risk of allergic reactions. It offers a molecular weight range of 0.70 - 1.0 x 10^6 Da, making it highly effective for skincare applications.
Why is Hyaluronic Acid important for anti-aging?
As we age, the natural levels of Hyaluronic Acid in our skin decline, which is associated with the appearance of fine lines and wrinkles. Young skin contains approximately twice as much Hyaluronic Acid compared to fifty-year-old skin. Maintaining adequate levels of Hyaluronic Acid helps retain skin elasticity and hydration, thereby reducing signs of aging and improving the overall texture and appearance of the skin.
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