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| Catalog Number | CI-SC-0045 |
| Product Name | Gluconolactone SB |
| CAS | 90-80-2 / 532-32-1 / 299-28-5 |
| Description | Natural broad-spectrum antimicrobial blend in powder form consisting of glucono-delta-lactone (microbial fermentation of corn) which has chelating and hydrating benefits and sodium benzoate (food grade preservative). Non-GMO. |
| Solubility | Water-soluble |
| Appearance | White powder |
| Application | All kinds of skin & hair care products (incl. emulsions, aqueous & anhydrous systems), sun care products, makeup products. |
| Storage | Store in a closed container at a dry place at room temperature |
| Composition | Gluconolactone, sodium benzoate, calcium gluconate |
| Features And Benefits | Effective broad spectrum protection for a wide range of skin and hair care productsActive in a wide pH range (best between pH 3-6)Has GRAS (Generally Accepted As Safe) status and is compliant with ECOCERT, WholeFoods and the European REACH regulation (Registration, Evaluation, Authorisation and restriction of Chemicals) |
| GMO | GMO-free |
| HS Code | 2906210000 |
| INCI | Gluconolactone, sodium benzoate, calcium gluconate |
| Manufacture | Proprietary blend of three antimicrobial agents. Gluconolactone is produced from an aqueous gluconic acid solution by dehydration involving azeotropic distillation with alcohols, followed by crystallization from the alcohol-containing residue. Calcium gluconate is produced by neutralization of gluconic acid with lime. Sodium benzoate is produced by the neutralization of benzoic acid with sodium bicarbonate. |
| Purity Grade | No purity grade applicable |
| Raw Material Source | Gluconic acid, benzoic acid |
| Uses | Recommended use level of 0.75-2.0%. Performs best in pH 3-6. Compatible with practically all raw materials. Can be added directly to the formulation below 100°F/40°C. For external use only. |
Jarząbek-Perz S, et al. Journal of Cosmetic Dermatology, 2023, 22(12), 3305-3312.
Gluconolactone (GLA) has antioxidant, moisturizing properties, as well as a soothing effect, protecting elastin fibers from UV-induced degradation and improving the function of the skin barrier. This work evaluated the effect of a series of 10% and 30% GLA chemical peels on skin parameters such as pH, transepidermal water loss (TEWL), and sebum levels.
Experimental methods and results
· Participants in the study included 16 women, with three split-face procedures carried out on each person's face using varying concentrations of GLA solution. Skin parameters were assessed both before the treatments and seven days following the final procedure at four different sites on each side of the face, including the forehead, eye area, cheek, and nose wing.
· The results indicated notable changes in sebum levels on the cheeks following the treatments. pH levels were consistently lower after each treatment at all measurement areas. TEWL levels were significantly reduced around the eyes, left forehead, and right cheek post-treatment. The study did not find any significant differences between the effects of differing concentrations of the GLA solution.
· Overall, the findings demonstrate that GLA plays a significant role in decreasing skin pH and TEWL levels, while also possessing sebum-regulating properties.
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