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| Catalog Number | CI-FC-0028 |
| Product Name | Gluconolactone |
| CAS | 4253-68-3 |
| Structure |  |
| Synonyms | (3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-one |
| IUPAC Name | (3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-one |
| Molecular Weight | 178.14 g/mol |
| Molecular Formula | C6H10O6 |
| InChI | InChI=1S/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1 |
| InChI Key | PHOQVHQSTUBQQK-SQOUGZDYSA-N |
| Melting Point | 160 °C |
| Appearance | Solid |
| Isomeric SMILES | C([C@@H]1[C@H]([C@@H]([C@H](C(=O)O1)O)O)O)O |
Gluconolactone, also known as Glucono-delta-lactone, is a versatile and naturally occurring poly-hydroxy acid (PHA) with numerous applications in skincare due to its gentle yet effective properties. In aqueous solutions, it partially converts to gluconic acid, creating an equilibrium that facilitates mild exfoliation by removing dead, pigmented, and dull skin cells, akin to AHAs and BHAs, but with minimal irritation. The multiple hydroxy groups in its structure endow it with hydrating capabilities similar to sugars, enhancing skin moisture by acting as a humectant, thereby improving elasticity, volume, and smoothing fine lines and wrinkles. Moreover, Gluconolactone supports skin recovery by strengthening the barrier function and revitalizing cells while providing robust antioxidant protection against free radicals. Additionally, it serves as a chelating agent, effectively sequestering heavy metal ions from the skin's surface, thus offering an alternative to traditional chelating agents like EDTA. This safe and multi-functional ingredient effectively balances pH in formulations and ultimately enhances skin vitality, revealing a luminous and youthful complexion.
What is Gluconolactone, and how is it used in skincare?
Gluconolactone, also known as Glucono-delta-lactone, is a cyclic ester of D-gluconic acid that appears as a white crystalline powder. It is commonly used in skincare products due to its exfoliating, chelating, and hydrating properties. Gluconolactone acts similarly to AHAs and BHAs but provides a gentler exfoliation without irritation, making it suitable for sensitive skin.
How does Gluconolactone benefit the skin?
Gluconolactone provides several skincare benefits, including gentle exfoliation, hydration, and antioxidant protection. It helps eliminate dead, pigmented, and dull skin cells, enhances skin hydration by attracting water, and protects skin cell membranes and DNA from oxidative damage. These combined effects result in a smoother, more hydrated skin surface with reduced fine lines and wrinkles.
Is Gluconolactone suitable for all skin types?
Yes, Gluconolactone is considered suitable for all skin types, including sensitive skin. Its gentle exfoliating properties allow it to remove dead cells without causing the irritation often associated with stronger exfoliants like AHAs and BHAs, making it an excellent option for those with more delicate skin.
Can Gluconolactone replace other skincare ingredients like EDTA?
In skincare formulations, Gluconolactone can be used as a chelating agent alternative to other compounds such as di- or tetrasodium EDTA. It effectively creates complexes with metal ions, helping to eliminate heavy metal particles from the skin surface. This makes it a versatile and naturally occurring choice for enhancing skincare product efficacy.
What makes Gluconolactone a good hydrator?
Gluconolactone is an effective hydrator due to its multiple hydroxy groups, which exhibit water-attracting properties similar to sugars. These humectant properties help to provide volume, elasticity, and density to the skin, resulting in optimal hydration, smoother skin, and the reduction of fine lines and wrinkles.
Does Gluconolactone offer any protective effects?
Yes, Gluconolactone provides protective effects by conditioning the skin, improving barrier function, and accelerating recovery processes. Additionally, it energizes and revives skin cells while scavenging free radicals, thus protecting against oxidative damage. Its low pH also helps balance acidity in water-based formulations, contributing to overall skin health.
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