Our customer service representatives are available 24 hours a day, from Monday to Sunday.
| Catalog Number | CI-GU-0085 |
| Product Name | Epigallocatechin Gallate |
| CAS | 989-51-5 |
| Structure |  |
| Synonyms | (-)-Epigallocatechin gallate;Benzoic acid, 3,4,5-trihydroxy-, 3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, (2R-cis)-;EGCG |
| IUPAC Name | [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate |
| Molecular Weight | 458.37 g/mol |
| Molecular Formula | C22H18O11 |
| InChI | InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1 |
| InChI Key | WMBWREPUVVBILR-WIYYLYMNSA-N |
| Melting Point | 222-224 °C |
| Purity | 95% |
| Density | 1.9 g/mL |
| Appearance | Solid |
| Highest Usage In Residency Products | 0.005 |
| Highest Usage In Rinsing Products | 0.0125 |
| Isomeric SMILES | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O |
| pKa | 7.75±0.25 |
Epigallocatechin Gallate (EGCG), a prominent catechin derived from green tea, is recognized for its remarkable antioxidant, anti-inflammatory, and antimicrobial properties. As a key component, comprising about 50% of the catechins in green tea, EGCG has been extensively studied for its health-preserving effects. It is a natural ingredient that can be easily incorporated into topical skin and hair care products due to its free radical scavenging capabilities. These reactive species, generated during normal metabolic processes or from environmental factors such as UV exposure and pollution, can damage cellular structures. EGCG helps mitigate this damage, thereby maintaining the skin's natural firmness and elasticity by preserving collagen and inhibiting enzymes that degrade it. Furthermore, EGCG supports skin microbiota balance and reduces acne by inhibiting bacterial growth. Beyond skincare, EGCG shows promise in reducing body fat, enhancing adipocyte metabolism, increasing fat oxidation, and promoting energy expenditure, making it a valuable addition to anti-cellulite formulations.
What are the benefits of Epigallocatechin Gallate (EGCG) found in green tea?
EGCG is a major catechin in green tea and is known for its powerful antioxidant, anti-inflammatory, and antimicrobial properties. It helps to scavenge free radicals, which are harmful species that can damage cell membranes and DNA. This antioxidant activity is beneficial in preserving skin health, reducing cancer risk, and maintaining overall well-being. EGCG also supports the preservation of collagen, skin's natural firmness, and elasticity, while balancing skin microbiota to prevent acne. Additionally, it may aid in reducing body fat and enhancing metabolism, which can be beneficial in anti-cellulite treatments.
How does EGCG contribute to skin health?
EGCG helps protect and maintain skin health in several ways. It acts as a formidable antioxidant, neutralizing free radicals that contribute to skin aging and damage. By preserving collagen and inhibiting collagen-destructing enzymes like MMP-1, EGCG helps maintain skin firmness and elasticity. Moreover, it balances the skin's microbiota and inhibits bacterial activity, reducing the risk of acne and other skin issues. As a natural ingredient, it is easy to add to topical skin care formulations, enhancing their protective and rejuvenating effects.
Can EGCG be used in hair care products, and what benefits does it provide?
Yes, EGCG can be used in hair care products. Its antioxidant properties help protect hair follicles from oxidative stress caused by environmental factors like UV exposure and pollution. This protection can lead to healthier hair and scalp, promoting hair growth and reducing hair loss. EGCG's anti-inflammatory and antimicrobial activities also support a balanced scalp environment, reducing issues like dandruff and scalp irritation.
How does EGCG affect body fat and metabolism?
EGCG may assist in reducing body fat and improving metabolism by enhancing fat oxidation and promoting energy expenditure. These effects position EGCG as a promising component in anti-cellulite formulations and weight management regimens, helping to improve body composition by encouraging the breakdown and utilization of fat stores.
Is there scientific evidence supporting the health benefits of EGCG?
Yes, numerous scientific studies have supported the health benefits of EGCG. Research has documented its role in preserving skin's collagen and elasticity, reducing free radical damage, and balancing skin microbiota. Studies also highlight its potential in reducing body fat and enhancing metabolism, making it a multifaceted compound with numerous health applications.
If you have any questions, please contact us. You will get a satisfactory answer.
