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| Catalog Number | CI-GU-0062 |
| Product Name | Dimethylmethoxy Chromanol |
| CAS | 83923-51-7 |
| Structure |  |
| Synonyms | 3,4-Dihydro-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-ol |
| Molecular Weight | 208.25 g/mol |
| Molecular Formula | C12H16O3 |
| Boiling Point | 329.0±42.0 °C |
| Purity | 95% |
| Density | 1.106 g/mL |
| Appearance | Solid |
| Highest Usage In Residency Products | 0.03 |
| pKa | 10.59±0.40 |
Dimethylmethoxy Chromanol is a highly effective molecule designed to combat a wide range of radicals, offering protection against reactive species and delaying premature skin aging. This compound efficiently neutralizes Reactive Nitrogen Species (RNS) and Reactive Oxygen Species (ROS), which are known to damage the skin's lipid barrier, cell DNA, and vital enzymes. Among these, peroxynitrite is notably associated with lipid peroxidation and cellular damage. Studies comparing antioxidant efficacy demonstrate that Dimethylmethoxy Chromanol surpasses well-known skincare ingredients like Tocopherol (Vitamin E), Resveratrol, and BHT in its ability to neutralize radicals. Furthermore, this compound uniquely scavenges both nitrogen and oxygen radicals and exhibits exceptional long-term stability, retaining and even enhancing its antioxidant properties over time, unlike many other antioxidants that degrade when stored in solution.
How effective is Dimethylmethoxy Chromanol as an antioxidant?
Dimethylmethoxy Chromanol is an exceptionally powerful antioxidant. At a concentration of 0.05%, it demonstrates an antioxidative capacity 82 times greater than Butylated Hydroxytoluene (BHT), a well-known antioxidant. This superior capability highlights its effectiveness in protecting against oxidative stress and neutralizing potentially damaging reactive species.
How does Dimethylmethoxy Chromanol compare to other antioxidants like Resveratrol?
In oxidative stress assays, Dimethylmethoxy Chromanol has shown a higher antioxidative power compared to other notable cosmetic antioxidants such as Resveratrol. Its dual activity makes it a leading choice for products aimed at combating oxidative damage and is a top contender among the most acclaimed antioxidants in the market.
What are the benefits of using Dimethylmethoxy Chromanol in skincare formulations?
When used in skincare formulations, Dimethylmethoxy Chromanol provides significant protection to human dermal fibroblasts, with studies indicating an 80% improvement in cell viability under oxidative stress conditions. This protective effect not only enhances the overall durability and defense of the skin but also aids in maintaining a youthful and healthy appearance.
What makes Dimethylmethoxy Chromanol a preferred ingredient in antioxidant formulations?
Dimethylmethoxy Chromanol is preferred in antioxidant formulations due to its high efficacy at low concentrations. Its unparalleled ability to neutralize reactive species and protect human cells sets it apart in the field of skincare antioxidants, making it an attractive ingredient for products designed to protect and repair skin from environmental stressors.
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