Our customer service representatives are available 24 hours a day, from Monday to Sunday.
| Catalog Number | CI-BP-0025 |
| Product Name | Conotoxin |
| CAS | 936616-33-0 |
| Structure |  |
| Synonyms | Mu-conotoxin |
| Molecular Weight | 2375.7 g/mol |
| Molecular Formula | C92H139N35O28S6 |
| Purity | 0.95 |
| Density | 1.71 g/mL |
| Appearance | White powder |
| Storage | -15~-20 °C |
| Safety | No heavy metals, no skin and eye irritation |
Conotoxin, specifically s-Mu-Conotoxin CnIIIC, is a refined oligopeptide sourced from the venom of marine cone snails, renowned for its targeted muscle relaxation properties. Derived from the Conus consors species, this 22-amino-acid conotoxin polypeptide demonstrates significant potential in therapeutic applications, particularly due to its ability to selectively inhibit NaV 1.4 sodium channels located in muscle tissue. Unlike other sodium channel subtypes, such as those found in the heart or nerves, NaV 1.4 channel inhibition leads to muscle relaxation without compromising cardiac or neurological function. This specificity makes s-Mu-Conotoxin CnIIIC an ideal component for advanced skincare formulations, where it can deliver a Botox-like effect by reducing facial muscle contractions and smoothing wrinkles, all through topical application without the need for injections or invasive methods.
What is s-Mu-Conotoxin CnIIIC, and where is it derived from?
s-Mu-Conotoxin CnIIIC is a synthetic oligopeptide derived from the toxins of marine cone snails. Specifically, it is obtained from a species known as Conus consors. The peptide consists of 22 amino acids and is part of the conotoxin family, also known as conopeptides.
How does s-Mu-Conotoxin CnIIIC work in the human body?
This conotoxin works by selectively blocking the NaV 1.4 sodium channels, which are primarily distributed in muscle tissue. These channels play a crucial role in transmitting electrical signals from neurons to muscles, facilitating muscle contraction. By blocking these channels, s-Mu-Conotoxin CnIIIC effectively relaxes muscles, mimicking a Botox-like effect to reduce mimic wrinkles in facial muscles.
Is s-Mu-Conotoxin CnIIIC safe for use in humans?
Ys, s-Mu-Conotoxin CnIIIC is considered safe for use in humans due to its high selectivity for NaV 1.4 sodium channels in muscles. Unlike many other toxins, it does not affect other critical sodium channels, such as NaV 1.5 in the heart or neuronal NaV 1.6-1.7, thus minimizing the risk of adverse effects on other organs and tissues.
What are the potential applications of s-Mu-Conotoxin CnIIIC in skincare?
In skincare, s-Mu-Conotoxin CnIIIC is used for its anti-aging properties. It can be applied topically to relax facial muscles, thereby reducing mimic wrinkles and providing a Botox-like effect without the need for injections or invasive procedures. This makes it a valuable ingredient in high-end skincare products targeting aging signs.
Does s-Mu-Conotoxin CnIIIC have any side effects?
Due to its specificity for muscle sodium channels and lack of interaction with other sodium channel subtypes, s-Mu-Conotoxin CnIIIC has a reduced risk of side effects. However, as with any bioactive compound applied to the skin, it is always recommended to conduct a patch test and use under professional guidance, especially for those with sensitive skin or those prone to allergic reactions.
If you have any questions, please contact us. You will get a satisfactory answer.
