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Chrysin

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Catalog Number	CI-OT-0043
Product Name	Chrysin
CAS	480-40-0
Structure
Synonyms	5,7-Dihydroxy-2-phenyl-4H-chromen-4-one
IUPAC Name	5,7-dihydroxy-2-phenylchromen-4-one
Molecular Weight	254.24 g/mol
Molecular Formula	C15H10O4
InChI	InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H
InChI Key	RTIXKCRFFJGDFG-UHFFFAOYSA-N
Boiling Point	357.5 °C
Melting Point	284-286 °C
Purity	0.98
Density	1.27 g/mL
Appearance	Yellow powder
Highest Usage In Residency Products	0.025
Isomeric SMILES	C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
pKa	6.50±0.40

Product Overview

Chrysin, a flavonoid present in honey, propolis, and numerous medicinal and edible plants such as passionfruit, carrot, mushroom, and chamomile, offers a range of benefits for the skin, notably its antioxidant, anti-inflammatory, and detoxification properties. It effectively scavenges free radicals, safeguarding skin cell membranes and DNA from oxidative stress and UV-induced damage. Additionally, chrysin alleviates irritation and has proven efficacy in treating skin conditions like atopic dermatitis due to its anti-inflammatory effects. It promotes the production of detoxification enzymes (UDP-glucuronosyltransferases or UGTs), which play a crucial role in binding and removing toxins from the body. This detoxifying action is particularly beneficial in addressing undereye dark circles, as it enhances the natural elimination of bilirubin, a pigment that can accumulate when UGTs are not functioning optimally. By stimulating UGT synthesis, chrysin aids in the effective removal of bilirubin while also reducing inflammation caused by excess iron-containing proteins, leading to a visible improvement in skin appearance.

Custom Q&A

What are the primary sources of Chrysin, and what benefits does it offer for skin health?

Chrysin is a flavonoid found in honey, propolis, and various medicinal and edible plants such as passionfruit, carrot, mushroom, and chamomile. It offers multiple skin health benefits, including antioxidant, anti-inflammatory, and detoxification effects. As an antioxidant, Chrysin scavenges free radicals, protecting skin cell membranes and DNA from oxidative stress and UV-induced damage. It also soothes irritation and helps manage skin conditions like atopic dermatitis due to its anti-inflammatory properties.

How does Chrysin help in the treatment of undereye dark circles?

Chrysin facilitates the treatment of undereye dark circles through its detoxifying action. It enhances the production of detoxification enzymes known as UDP-glucuronosyltransferases (UGTs), which are responsible for conjugating and eliminating toxins like bilirubin from the body. By increasing UGT activity, Chrysin boosts the local elimination of bilirubin and other pigments deposited around the eyes, reducing the appearance of dark circles. Additionally, it soothes the inflammation caused by excess iron-containing proteins, further improving the skin's appearance.

Can Chrysin be used for skin conditions other than dark circles?

Yes, Chrysin is beneficial for several skin conditions beyond dark circles. Its potent anti-inflammatory properties make it an effective remedy for conditions like atopic dermatitis. By soothing skin irritation and reducing inflammation, Chrysin can help alleviate the symptoms associated with various dermatological issues, promoting healthier skin.

How does Chrysin contribute to the detoxification process in the skin?

Chrysin contributes to skin detoxification by enhancing the synthesis of detoxification enzymes, specifically UDP-glucuronosyltransferases (UGTs). These enzymes play a crucial role in binding and eliminating toxins, including bilirubin, from the body. By boosting UGT production, Chrysin promotes the effective removal of toxic substances that can accumulate in the skin, supporting overall skin health and clarity.

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