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| Catalog Number | CI-GU-0067 |
| Product Name | Carnosic Acid |
| CAS | 3650-09-7 |
| Structure |  |
| Synonyms | (4aR,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-4a-carboxylic Acid |
| IUPAC Name | (4aR,10aS)-5,6-dihydroxy-1,1-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-4a-carboxylic acid |
| Molecular Weight | 332.4 g/mol |
| Molecular Formula | C20H28O4 |
| InChI | InChI=1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1 |
| InChI Key | QRYRORQUOLYVBU-VBKZILBWSA-N |
| Boiling Point | 506.4±50.0 °C |
| Melting Point | 190 °C |
| Purity | 95% |
| Density | 1.18 g/mL |
| Appearance | Solid |
| Highest Usage In Residency Products | 0.0002 |
| Isomeric SMILES | CC(C)C1=C(C(=C2C(=C1)CC[C@@H]3[C@@]2(CCCC3(C)C)C(=O)O)O)O |
What is the chemical formula of Carnosic Acid?
The chemical formula of Carnosic Acid is C20H28O4.
What are some synonyms of Carnosic Acid?
Some synonyms of Carnosic Acid include CARNOSOLIC ACID and salvin.
What are some of the chemical properties of Carnosic Acid?
The melting point of Carnosic Acid is 190°C, and it is a yellow powder. It is slightly soluble in chloroform and methanol.
Where is Carnosic Acid commonly found?
Carnosic Acid is abundant in sage and rosemary leaves.
What are the main properties and uses of Carnosic Acid?
Carnosic Acid has antioxidative, anti-inflammatory, anti-microbial, and neuroprotective properties. It is used as the main active antioxidant in food additives and cosmetic products.
What is the usage of Carnosic Acid in the cosmetic industry?
Carnosic Acid is used in hair care and skin care products in the cosmetic industry.
What is the role of Carnosic Acid in oral health care according to in vitro studies?
In vitro studies have shown that Carnosic Acid efficiently protects against typical cariogenic microorganisms in oral health care.
What is the antineoplastic effect of Carnosic Acid?
Carnosic Acid exhibits anti-proliferative effects in human renal carcinoma cells and cervical carcinoma cells. It induces apoptosis in cancer cells through ER stress.
How does Carnosic Acid protect against oxidation in fats and oils?
Carnosic Acid inhibits the free-radical chain reaction that leads to the oxidation of fats and oils, thereby stabilizing and increasing the shelf life of meats.
What is the role of ROS scavengers in Carnosic Acid-induced apoptosis?
ROS scavengers inhibit the ATF4 and CHOP expression induced by Carnosic Acid, indicating that ER stress plays a significant role in the apoptosis of cancer cells induced by Carnosic Acid.
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