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Butylene Glycol (CAS 107-88-0)

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Catalog Number CI-HC-0208
Product Name Butylene Glycol (CAS 107-88-0)
CAS 107-88-0
Structure
Description Butylene Glycol is a chemical compound with the molecular formula C4H10O2. It is a colorless, odorless, and viscous liquid that is commonly used as a solvent, humectant, and skin conditioning agent in various cosmetic and personal care products. Butylene Glycol helps to enhance the effectiveness of other ingredients in a product, while also helping to keep the product from drying out. It also has hydrating properties that help to keep skin moisturized and soft. In addition, Butylene Glycol is used as a preservative and a viscosity regulator in many products, including lotions, creams, and hair care products.
Appearance clear, odorless, and slightly viscous liquid
Application 1. As a skin-conditioning agent: Butylene glycol is commonly used in skincare and cosmetic products as a humectant, which helps to retain moisture and improve skin texture.
2. As a solvent: Butylene glycol is a versatile solvent that can be used to dissolve a wide range of compounds in both water-based and oil-based formulations.
3. As a viscosity modifier: Butylene glycol can be used to adjust the viscosity of formulations, making them thicker or thinner as required.
4. As a preservative: Butylene glycol has antimicrobial properties and can help to extend the shelf life of products by preventing the growth of bacteria and other microorganisms.
5. As a surfactant: Butylene glycol can be used as a surfactant to help emulsify and disperse oils and other hydrophobic substances in water-based formulas.
6. As a flavor or fragrance enhancer: Butylene glycol is commonly used in food and beverage applications as a flavor enhancer, and in personal care products as a fragrance enhancer.
Features And Benefits 1. Moisturizes the skin
2. Enhances the absorption of other skincare ingredients
3. Improves the texture and consistency of cosmetics
4. Acts as a humectant to help retain moisture in the skin
5. Has a soothing effect on irritated skin
6. Helps to increase the shelf life of cosmetics by preventing microbial growth
7. Has a lightweight and non-greasy consistency
Case Study

1,3-Butylene Glycol as a Solvent for the Preparation of PEG-Based Copolymer Cosmetic Films

Kaji M, et al. Journal of oleo science, 2017, 66(11), 1239-1245.

The surface morphology of cosmetic films composed of amphiphilic random copolymers (methoxy polyethylene glycol-23 methacrylate/glyceryl diisostearate methacrylate copolymer, MPM-GDM) and solvents was studied. The surface morphology was adjusted by changing the solvent composition of 1,3-butylene glycol (1,3-BG) (a good solvent for MPM-GDM) and glycerol (a poor solvent for MPM-GDM), thereby improving the functionality and feel of the cosmetic films.
Preparation procedure of mixtures for films
· For two or three-component mixtures, MPM-GDM and various solvents (water, methanol, ethanol, 2-propanol, 1-butanol, ethylene glycol, 1,3-BG, 1,4-BG, and glycerin) were mixed in a glass test tube using a vortex mixer or spatula for mixing viscous samples. The mixtures were then left to stand at 40°C for 2-7 days before cooling to room temperature.
· In the case of four or five-component mixtures, xanthan gum was mixed with solvents (1,3-BG and glycerin) in a glass test tube at room temperature. MPM-GDM was later added to the mixture, which was then heated above 40°C and stirred manually. Water was added, and the mixture was stirred with a magnetic stirrer for several hours before cooling to room temperature. The weight ratio of MPM-GDM to xanthan gum was either 1:0.05 or 1:0.01, with the total amount of solvents (excluding water) kept constant while varying the weight fraction.

Evaluation of the Preservative Effect of 1,3-Butylene Glycol and Alkane Diols in Cosmetics

Suh J Y, et al. Journal of the Society of Cosmetic Scientists of Korea, 2018, 44(4), 363-373.

In order to address the safety issues of paraben preservatives in cosmetics, this work evaluated the preservative effect of 1,3-butanediol, 1,2-hexanediol and 1,2-pentanediol as alternative paraben preservative systems.
Evaluation methods and results
· The effectiveness of 1,3-butylene glycol as a preservative in cosmetic creams was assessed by conducting a M-3 challenge test with concentrations ranging from 5% to 25%. Similar evaluations were also conducted on alkane diols such as 1,2-hexanediol and 1,2-pentanediol. The results of the study showed that 1,3-butylene glycol exhibited effective preservative properties against a variety of microbial strains (including S. aureus, E. coli, P. aeruginosa, C. albicans, and A. niger) at a concentration of 25%.
· Additionally, combinations of 0.3% phenoxyethanol and 0.1% ethylhexylglycerin were tested, as well as the efficacy of alkane diols like 1,2-hexanediol and 1,2-pentanediol as potential alternatives to phenoxyethanol. The results indicated that both 1,2-hexanediol and 1,2-pentanediol at a concentration of 1% exhibited preservative efficacy.
In conclusion, the combination of 25% 1,3-butylene glycol and 0.1% ethylhexylglycerin, as well as 1% 1,2-hexanediol and 1% 1,2-pentanediol, demonstrated the most effective preservative efficacy among all the compositions tested in the study.

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