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| Catalog Number | CI-SC-0567 |
| Product Name | Bakuchiol |
| CAS | 10309-37-2 / 7732-18-5 |
| Synonyms | 4-(3-Ethenyl-3,7-Dimethyl-1,6-Octadienyl)Phenol |
| Description | Retinol-like, 100% natural, anti-aging & anti-blemished skin compound extracted from the edible seeds of the Psoralea Corylifolia plant, a herb that is widely used in Indian as well as in Chinese medicine. Despite having no structural resemblance to retinol, Bakuchiol was found to have retinol functionality through retinol-like regulation of gene expression. > 99% purity. Molecular weight 256.38g/mol. Specific gravity <1.0. |
| Molecular Weight | 256.4 g/mol |
| Molecular Formula | C18H24O |
| Canonical SMILES | CC(=CCC[C@@](C)(C=C)/C=C/C1=CC=C(C=C1)O)C |
| Boiling Point | 391.38 °C (Predicted) |
| Purity | 97% |
| Solubility | Water-insoluble. Soluble in alcohol, DMSO, plant oils, triglyceride, silicone oils, and a wide-range of hydrophobic emollients. |
| Appearance | Light yellow to brown viscous liquid. |
| Application | Anti-blemish skin products, face creams, lotions, anti-aging & anti-wrinkle products. |
| Storage | Store at room temperature |
| Composition | Bakuchiol, water |
| Features And Benefits | Effective active agent against blemished and impure skin.Balances natural regulation of sebum production.Bakuchiol has anti-aging and anti-wrinkle properties by having retinol-like activities. Bakuchiol has been clinically demonstrated to reduce hyperpigmentation and wrinkles as efficiently as retinol.In in-vitro studies Bakuchiol has been found to stimulate collagen production and maintain the high level of elastin.Bakuchiol has excellent photochemical and hydrolytic stability and acts as stabilizer of retinol under photo-oxidative environment.In-vitro, Bakuchiol has anti-bacterial and anti-fungal activity. |
| GMO | GMO-free |
| HS Code | 3504001000 |
| INCI | Bakuchiol |
| Manufacture | Bakuchiol is extracted and purified from the seeds of the Psoralea corylifolia plant. |
| pH | see long description |
| Raw Material Source | Edible seeds of the Psoralea Corylifolia plant |
| Refractive Index | 1.56 (Predicted) |
| Uses | Add to the oil phase of emulsions. Do not heat to more than 50°C (122°F). Typical use level: 0.25 to 1%. Addition of a small amount of a chelating agent (e.g. 0.05% EDTA) is helpful in overcoming coloration issue due to the presence of iron or copper. pH of final product should be < 6.0. For external use only. |
Bakuchiol is a natural compound extracted from the seeds and leaves of the Psoralea corylifolia plant, and has been traditionally used in oriental medicine. This phenolic compound is recognized as the first natural alternative to retinol, offering similar anti-aging benefits without close structural resemblance to retinol itself. Notably, Bakuchiol effectively reduces hyperpigmentation and dark spots diminishes fine lines and wrinkles, and provides protection against free radical damage. It boasts impressive photochemical and hydrolytic stability and a favorable safety profile, making it suitable for various formulations due to its compatibility with numerous emollients and solubilizers. Empirical evidence from DNA microarray qtPCR cell culture and enzyme inhibitory activity studies as well as in vitro and in vivo research, particularly in acne-prone skin highlights, Bakuchiol's potential as a key ingredient in dermatological and skincare products. Preliminary findings suggest that Bakuchiol could replicate the skin-enhancing effects of retinol, avoiding its side effects thus potentially advancing the pursuit of youthful skin.
What is Bakuchiol and where does it come from?
Bakuchiol is a natural compound derived from the Psoralea corylifolia plant, which has been used in oriental medicine. It is recognized as the first natural alternative to retinol, offering similar benefits for skincare without close structural similarities. Known for its anti-aging properties, Bakuchiol is over 99% pure and extracted from the seeds and leaves of the plant.
How does Bakuchiol compare to Retinol in terms of effectiveness?
Although Bakuchiol and Retinol differ structurally, they share a similar pattern of activity on key anti-aging genes and proteins. Bakuchiol effectively reduces hyperpigmentation and dark spots, diminishes fine lines and wrinkles, and offers protective benefits against free radical damage. Its excellent photochemical and hydrolytic stability, alongside a favorable safety profile, makes it a compelling retinol alternative for skincare.
Can Bakuchiol irritate the skin like Retinol might?
Bakuchiol is known for its good safety profile and is less likely to cause the irritation often associated with Retinol. This makes it suitable for individuals with sensitive skin who are looking for an alternative that provides similar anti-aging benefits without the typical side effects.
What are the stability and formulation benefits of using Bakuchiol in skincare products?
Bakuchiol exhibits excellent photochemical and hydrolytic stability, which allows it to maintain effectiveness over time. It is also easy to formulate due to its compatibility with various emollients and solubilizers, making it a versatile ingredient in dermatological and skincare formulations.
What are the potential benefits of Bakuchiol for acne-prone skin?
Studies, including DNA microarray and qtPCR results, have demonstrated Bakuchiol's potential benefits for acne-prone skin. In vitro and in vivo studies indicate its ability to modulate enzyme activity and deliver retinol-like effects, making it a promising ingredient for improving skin appearance and health, specifically in acne management.
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