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| Catalog Number | CI-BP-0026 |
| Product Name | Acetyl tripeptide-30 citrulline |
| Application | It can be recommended to use in anti-stretch mark products. |
Acetyl Tripeptide-30 Citrulline, also known as Peptide AC29, is a synthetic peptide that effectively prevents the degradation of extracellular matrix components by inhibiting metalloproteinase (MMP) enzymes. Extensive in vitro studies have demonstrated its selective inhibition of various MMPs, highlighting its complete suppression of MMP-2 activity, which plays a crucial role in degrading type I collagen fibers-the predominant collagen type in the dermis. It also reduces the activity of MMP-9 by 63.1% and MMP-1 and MMP-3 by 35% to 40%. By preserving structural proteins and extracellular matrix components in the skin, Acetyl Tripeptide-30 Citrulline delivers significant firming, lifting, and anti-aging benefits. This peptide is a key ingredient in high-end skincare formulations and peptide-based complexes such as Vanistryl®, promoting extracellular matrix regeneration for a youthful and smoother skin appearance.
What is Acetyl Tripeptide-30 Citrulline and how does it function?
Acetyl Tripeptide-30 Citrulline, known as Peptide AC29 with the sequence Lys-α-Asp-Ile-Citrulline, is a synthetic peptide that inhibits metalloproteinase enzymes (MMPs) responsible for the degradation of extracellular matrix (ECM) components. By preventing this degradation, it helps maintain the skin's structural integrity and promotes a firmer and more youthful appearance.
How effective is Acetyl Tripeptide-30 Citrulline in inhibiting MMPs?
In vitro studies indicate that Acetyl Tripeptide-30 Citrulline is particularly effective in inhibiting MMP-2 activity, which is responsible for degrading type I collagen fibers, the most common collagen type in the dermis. It inhibits MMP-9 by 63.1% and MMP-1 and MMP-3 by 35% to 40%, contributing to its anti-aging and skin-firming effects.
What are the benefits of using skincare products containing Acetyl Tripeptide-30 Citrulline?
Skincare products featuring Acetyl Tripeptide-30 Citrulline are known to deliver substantial firming and lifting effects while helping preserve key structural proteins and ECM components. This results in a more youthful, supple, and smoother skin appearance due to enhanced ECM component regeneration.
In what types of products is Acetyl Tripeptide-30 Citrulline generally incorporated?
Acetyl Tripeptide-30 Citrulline is commonly incorporated into high-end skincare products and peptide-based complexes such as Vanistryl®. These products leverage the peptide's ability to enhance the regeneration of ECM components, aiming to provide anti-aging benefits and improve overall skin texture.
Is Acetyl Tripeptide-30 Citrulline safe for all skin types?
While specific safety evaluations are not mentioned in the reference, peptides like Acetyl Tripeptide-30 Citrulline are generally well-tolerated across various skin types due to their targeted mechanism of action. However, it's always advisable to conduct a patch test or consult with a dermatologist if you have sensitive skin or are prone to allergic reactions.
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