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Catalog Number | CI-BP-0191 |
Product Name | Acetyl hexapeptide-38 |
CAS | 1400634-44-7 |
Structure | |
IUPAC Name | (2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoic acid |
Molecular Weight | 701.8 g/mol |
Molecular Formula | C30H55N9O10 |
InChI | InChI=1S/C30H55N9O10/c1-13(2)20(26(45)35-18(10-9-11-33-30(31)32)24(43)39-23(16(7)41)29(48)49)37-28(47)22(15(5)6)38-27(46)21(14(3)4)36-25(44)19(12-40)34-17(8)42/h13-16,18-23,40-41H,9-12H2,1-8H3,(H,34,42)(H,35,45)(H,36,44)(H,37,47)(H,38,46)(H,39,43)(H,48,49)(H4,31,32,33)/t16-,18+,19+,20+,21+,22+,23+/m1/s1 |
InChI Key | BETZBTCJWHBFIG-JAAOUQFMSA-N |
Purity | 0.95 |
Appearance | White powder |
Storage | -15~-20 °C |
Isomeric SMILES | C[C@H]([C@@H](C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CO)NC(=O)C)O |
Safety | No heavy metals, no skin and eye irritation |
Acetyl Hexapeptide-38, also known by the trade name Adifyline®, is a synthetic peptide renowned for its application in cosmetic and skincare products. By enhancing the expression of PGC-1α, it boosts cellular energy metabolism and promotes the lipid storage capacity of mature adipocytes found in white adipose tissue. This property is crucial for increasing the volume of fatty tissue beneath the skin, making it a valuable component for products aimed at reshaping and remodeling specific body areas, such as the face, breasts, or buttocks. Its ability to smooth expression lines and wrinkles by enhancing skin volume contributes to a more lifted and youthful appearance. Acetyl Hexapeptide-38 is incorporated into various body care formulations to achieve a replenishing effect in areas like breasts and buttocks, thereby enhancing body contours. It is also utilized in facial redefining treatments, breast-firming products, anti-aging cosmetics, and specific makeup and care formulations for mature women, including lip care and products for the cleavage area, as well as hand treatments that target the loss of adipose tissue with age.
What is Acetyl Hexapeptide-38, and how does it function?
Acetyl Hexapeptide-38 is a synthetic peptide identified through advanced screening methods and gene assay techniques. It functions by increasing the expression of PGC-1α by 61.1%, which is crucial for cellular energy metabolism. It enhances lipid storage in adipocytes found in white adipose tissue and promotes adipocyte differentiation from subcutaneous preadipocytes. This ultimately leads to increased volume in targeted skin areas.
In what types of products is Acetyl Hexapeptide-38 typically used?
Acetyl Hexapeptide-38 is commonly used in various skin and body care products. It is incorporated into facial redefining preparations, breast-firming formulations, facial anti-aging products, lip care products, and makeup. Additionally, it is found in formulations specifically designed for the cleavage area and anti-aging hands products.
What benefits does Acetyl Hexapeptide-38 provide for skin care applications?
This peptide is known for its ability to increase fatty tissue volume beneath the skin in specific local areas, making it ideal for reshaping and remodeling problematic sites like the facial oval, breasts, and buttocks. It smooths expression lines and wrinkles by enhancing skin volume, thus offering a lifted, supple, and youthful appearance.
How does Acetyl Hexapeptide-38 contribute to body care?
In body care, Acetyl Hexapeptide-38 improves volume in targeted areas such as breasts and buttocks, providing a replenishing effect that delivers attractive body curves. This makes it a popular choice for products targeting these areas for contouring and firming purposes.
Is Acetyl Hexapeptide-38 suitable for anti-aging treatments?
Yes, Acetyl Hexapeptide-38 is highly suitable for anti-aging treatments. It is effective in reducing the appearance of wrinkles and smoothing expression lines in the face and other areas that lose adipose tissue with age, such as hands. Its ability to enhance skin volume and elasticity contributes significantly to a rejuvenated and youthful look.