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Pomegranate Seed Oil

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Catalog Number CI-SC-0492
Product Name Pomegranate Seed Oil
CAS 84961-57-9
Description Pomegranate seed oil is known to be rich in natural antioxidants and a quality source of the essential fatty acid Punicic (18:3 n-5). Clean carrier oil with a golden yellow appearance and characteristic fruity aroma. Extraction method: Cold pressed, filtered, virgin, unrefined.
Solubility Oil-soluble
Appearance Golden yellow liquid, characteristic fruity aroma
Application Skin care and hair products
Storage Store light-protected at a cool and dry place
HS Code 1518009000
INCI Punica Granatum (Pomegranate) seed oil
Uses Add to oil-phase of emulsions. Typical use level 1-20%. For external use only.
Product Overview

Pomegranate seed oil, extracted from the seeds of the Punica Granatum fruit, is renowned for its high concentration of beneficial compounds, making it a valuable addition to personal care products. Rich in conjugated linolenic acid, particularly punicic acid, this oil possesses unique fatty acid properties that significantly enhance its efficacy. It is abundant in antioxidants and essential nutrients such as Vitamin C, folic acid, and vital minerals like calcium, potassium, and iron. These components contribute to cellular regeneration, particularly benefiting the epidermis and dermis layers of the skin. Pomegranate seed oil also combats free radicals, supports wound healing, strengthens the immune system, and exhibits anti-inflammatory properties, all contributing to skin rejuvenation. Additionally, the presence of phytohormones, including Coumestrol and Estrone, as well as its potential anti-carcinogenic effects as identified in scientific studies, further emphasize its therapeutic capabilities. Consequently, pomegranate seed oil is particularly suited for anti-aging formulations and skincare products targeting mature skin.

Case Study

Improvement Effect of Pomegranate Seed Oil Extract on Skin Inflammation

Hamouda, Asmaa Fathi, et al. Molecules, 2023, 28(2), 903.

This work aimed to evaluate the effects of Avocom-M cream and pomegranate seed oil extract (PSOE) on neurally mediated skin inflammation in animals and humans.
Experimental design and evaluation results
· The effects of PSOE and Avocom-M treatment on phenobarbital- and formaldehyde-induced biochemical changes in rat models were studied, respectively. Parallel observations were conducted in human volunteers who received TROSYD (1% Tioconazole Dermal Cream) and PSOE as interventions for skin inflammation. The effects of PSOE and Avocom-M treatment on phenobarbital- and formaldehyde-induced skin inflammation markers in rats were studied. Changes in the levels of these inflammatory markers were also studied in human volunteers who received TROSYD and PSOE anti-inflammatory treatment and those who did not receive treatment, respectively, and the results were compared with those from rat studies.
· Treatment with PSOE and Avocom-M improved skin condition in rats, counteracting the effects of phenobarbital and formaldehyde. Significant improvements were observed in human skin reports after experimental PSOE and TROSYD treatment. PSOE treatment has beneficial effects on collagenase, elastase, hyaluronidase, tyrosinase, nitric oxide (NO), malondialdehyde (MDA), and cyclooxygenase 2 (COX-2) levels in human skin. This may be due to the phytochemicals of pomegranate seed oil and the chemicals of Avocom-M and TROSYD creams.

Pomegranate Seed Oil Enhances Transdermal Absorption of trans-Resveratrol

Liu, Wei, et al. Journal of Oleo Science, 2018, 67(4), 479-487.

Pomegranate seed oil (PSO) has the potential to act as a transdermal enhancer, e.g. to promote the transdermal absorption of resveratrol. The effect of PSO in promoting transdermal absorption of resveratrol was studied and compared with isopropyl palmitate (IP).
· The findings indicate that the total amount of drugs with 2.5%, 5.0%, and 10% PSO absorbed through the skin is 1.25, 2.25, and 3.14 times greater than that of resveratrol by itself.
· Moreover, different concentrations of PSO accelerated the penetration of resveratrol into the skin throughout the entire process, showing a better ability than IP in enhancing the transdermal absorption of resveratrol.
· Furthermore, 2.5% IP significantly increased resveratrol retention in the stratum corneum (SC), epidermis, and dermis (p < 0.05), whereas 2.5% PSO only increased drug retention in the SC.
· The involvement of oils also helps the diffusion of resveratrol within the skin. Both IP and PSO promoted transdermal transport of resveratrol. PSO may be a more promising oil phase for the preparation of resveratrol transdermal absorption microemulsions.

Custom Q&A

What are the main benefits of using Pomegranate Seed Oil for skincare?

Pomegranate Seed Oil, also known as Punica Granatum Seed Oil, offers several benefits for skincare. It is an excellent antioxidant, making it ideal for anti-aging applications. It helps protect the skin against harmful UV exposure, free radicals, and environmental stress. Additionally, it supports the skin's natural protective systems by acting as a radical scavenger.

How does Pomegranate Seed Oil protect the skin from UV exposure and free radicals?

Pomegranate Seed Oil provides a protective barrier for the skin against UV exposure and free radicals through its antioxidant properties. These properties help neutralize harmful free radicals and reduce oxidative stress, which can be damaging to the skin.

Can Pomegranate Seed Oil improve the skin's barrier function?

Yes, when applied topically, Pomegranate Seed Oil can enhance the skin's barrier function. The gamma-linolenic acid present in the oil penetrates the lipid layers of the skin, which in turn improves the skin's ability to retain moisture and reduces transepidermal water loss.

Is Pomegranate Seed Oil suitable for all skin types?

Pomegranate Seed Oil is generally well-suited for various skin types due to its soothing and protective properties. However, as with any skincare product, it's recommended to perform a patch test beforehand to ensure personal compatibility, especially for sensitive or reactive skin types.

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