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Tripeptide-10 citrulline

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Catalog Number	CI-BP-0079
Product Name	Tripeptide-10 citrulline
CAS	960531-53-7
Synonyms	L-Lysyl-L-alpha-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-L-ornithinamide
IUPAC Name	(3S)-4-[[(2S,3S)-1-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2,6-diaminohexanoyl]amino]-4-oxobutanoic acid
Molecular Weight	530.62 g/mol
Molecular Formula	C22H42N8O7
InChI	InChI=1S/C22H42N8O7/c1-3-12(2)17(21(36)28-14(18(25)33)8-6-10-27-22(26)37)30-20(35)15(11-16(31)32)29-19(34)13(24)7-4-5-9-23/h12-15,17H,3-11,23-24H2,1-2H3,(H2,25,33)(H,28,36)(H,29,34)(H,30,35)(H,31,32)(H3,26,27,37)/t12-,13-,14-,15-,17-/m0/s1
InChI Key	GKPMARPRXONRJX-BWJWTDLKSA-N
Boiling Point	965.2±65.0 °C
Purity	0.95
Density	1.252 g/mL
Appearance	White powder
Storage	-15~-20 °C
Isomeric SMILES	CC[C@H](C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)N
pKa	4.15±0.10
Safety	No heavy metals, no skin and eye irritation

Product Overview

Tripeptide-10 citrulline is a peptide designed to enhance skin's structural integrity by mimicking the natural functions of decorin, a critical protein that influences collagen organization. Over time, the natural aging process alters decorin, impacting its ability to regulate collagen fibril size and distribution, which results in diminished skin firmness and elasticity. By emulating the actions of decorin, Tripeptide-10 citrulline effectively supports the maintenance of collagen organization and restores the skin's suppleness and resilience. In scientific studies, formulations containing Tripeptide-10 citrulline demonstrated a notable 54% improvement in skin suppleness within 28 days.

Custom Q&A

What are the primary benefits of using Tripeptide-10 citrulline in skincare?

Tripeptide-10 citrulline offers several benefits for the skin, including the regulation of fibrillogenesis and control over collagen fibril growth. It enhances skin suppleness by promoting better cohesion of collagen fibers, which increases resiliency and improves the overall appearance of the skin.

How does Tripeptide-10 citrulline help with mature skin?

For mature skin, Tripeptide-10 citrulline compensates for the lack of decorin, a protein that decreases with age. It binds to collagen fibrils, regulates their organization, and enhances their stability, ensuring the skin maintains its shape and suppleness.

Can Tripeptide-10 citrulline improve the uniformity of collagen fibrils?

Yes, Tripeptide-10 citrulline ensures uniformity in fibril diameter and regular spacing of collagen fibrils, which is crucial for maintaining the structural integrity and resilience of the skin tissue.

Does Tripeptide-10 citrulline provide moisturizing benefits?

Tripeptide-10 citrulline has a high and sustained moisturizing profile, which helps maintain the skin's hydration levels and further contributes to its suppleness and health.

Is Tripeptide-10 citrulline alone sufficient for collagen boosting in skincare?

While Tripeptide-10 citrulline is effective in boosting collagen, it is only one part of the solution. It is essential to ensure that new collagen fibrils are well-oriented, organized, and uniform to achieve optimal skin health and appearance.

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