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Stearyl Glycyrrhetinate

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Catalog Number CI-OT-0040
Product Name Stearyl Glycyrrhetinate
CAS 13832-70-7
Structure
Synonyms Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, octadecyl ester, (3beta,20beta)-
IUPAC Name octadecyl (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylate
Molecular Weight 723.2 g/mol
Molecular Formula C48H82O4
InChI InChI=1S/C48H82O4/c1-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-33-52-42(51)45(5)30-29-44(4)31-32-47(7)36(37(44)35-45)34-38(49)41-46(6)27-26-40(50)43(2,3)39(46)25-28-48(41,47)8/h34,37,39-41,50H,9-33,35H2,1-8H3/t37-,39-,40-,41+,44+,45-,46-,47+,48+/m0/s1
InChI Key WNIFXKPDILJURQ-JKPOUOEOSA-N
Boiling Point 732.5±60.0 °C
Melting Point 70-77 °C
Purity 95%
Density 1.01 g/mL
Appearance Solid
Highest Usage In Residency Products 0.02
Isomeric SMILES CCCCCCCCCCCCCCCCCCOC(=O)[C@]1(CC[C@@]2(CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2C1)C)C)C
Product Overview

Stearyl Glycyrrhetinate, a derivative of glycyrrhizic acid, is a versatile ingredient esteemed for its enhanced oil solubility, making it suitable for a wide array of cosmetic formulations. This white or yellowish-white powder shares the beneficial properties of glycyrrhetinic acid, notably its anti-inflammatory, soothing, antibacterial, and skin-conditioning effects. It is particularly effective in reducing skin inflammation and irritation, especially following sun exposure. Consequently, Stearyl Glycyrrhetinate is commonly incorporated into creams, lotions, sun care and after-sun care products, as well as lipsticks and makeup, with typical usage levels ranging from 0.1% to 0.5%.

Custom Q&A

What is Stearyl Glycyrrhetinate?

Stearyl Glycyrrhetinate is a derivative of glycyrrhizin, appearing as a white or yellowish-white powder. It is known for its enhanced oil solubility, which makes it suitable for a wide range of cosmetic formulations. It is particularly valued for its effective anti-inflammatory properties.

How does Stearyl Glycyrrhetinate benefit skincare products?

As a soothing, antibacterial, and skin-conditioning ingredient, Stearyl Glycyrrhetinate is used to reduce skin inflammation and irritation, especially after sun exposure. This makes it a popular additive in products designed to comfort and repair the skin.

In what types of products is Stearyl Glycyrrhetinate typically used?

Stearyl Glycyrrhetinate can be found in various creams, lotions, sun care and after-sun care products, as well as in lipsticks and makeup. Its versatility in formulation makes it a common choice in products aimed at soothing and protecting the skin.

What is the recommended usage level of Stearyl Glycyrrhetinate in formulations?

The typical usage level of Stearyl Glycyrrhetinate in cosmetic formulations ranges from 0.1% to 0.5%. This range is sufficient to leverage its beneficial properties without compromising the integrity of the product.

Can Stearyl Glycyrrhetinate cause skin irritation?

Generally, Stearyl Glycyrrhetinate is recognized for its ability to soothe and diminish irritation, rather than cause it. However, as with any ingredient, users with sensitive skin should patch-test new products and consult with a dermatologist if there are concerns.

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