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| Catalog Number | CI-OT-0049 |
| Product Name | Sphinganine |
| CAS | 764-22-7 |
| Structure |  |
| Synonyms | (R-(R*,S*))-2-Aminooctadecane-1,3-diol;1,3-Octadecanediol, 2-amino-, (2S,3R)- |
| IUPAC Name | (2S,3R)-2-aminooctadecane-1,3-diol |
| Molecular Weight | 301.5 g/mol |
| Molecular Formula | C18H39NO2 |
| InChI | InChI=1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1 |
| InChI Key | OTKJDMGTUTTYMP-ZWKOTPCHSA-N |
| Boiling Point | 446.2±25.0 °C |
| Melting Point | 70-72 °C |
| Purity | 95% |
| Density | 0.93 g/mL |
| Appearance | Solid |
| Highest Usage In Residency Products | 0.004 |
| Isomeric SMILES | CCCCCCCCCCCCCCC[C@H]([C@H](CO)N)O |
| pKa | 12.57±0.45 |
Sphinganine, produced through a sustainable biotechnological process, acts effectively in the management of hair health by inhibiting the enzyme 5-alpha-reductase. This inhibition is crucial in reducing dihydrotestosterone (DHT) levels within hair follicles, thereby mitigating hair loss and fostering growth by prolonging the anagen phase of the hair life cycle. This compound enhances hair quality and texture, akin to topical Finasteride, yet without its typical side effects. In addition to its role in hair growth, Sphinganine exhibits anti-microbial properties, effectively reducing Malassezia furfur populations, decreasing scalp oiliness, and preventing dandruff. It further supports scalp health by restoring microflora balance, which is fundamental for maintaining healthy hair.
What is Sphinganine, and how does it help with hair loss?
Sphinganine is a sphingolipid obtained through a sustainable biotechnological process. It aids in the prevention of hair loss by directly inhibiting the enzyme 5-alpha-reductase. This enzyme is responsible for converting testosterone into dihydrotestosterone (DHT), which is a major factor in hair follicle miniaturization and hair thinning. By reducing DHT levels, Sphinganine helps to maintain the hair in its anagen (growth) phase for longer, thereby promoting hair growth and improving the quality and appearance of hair strands.
How is Sphinganine different from other hair loss treatments like Finasteride?
Unlike Finasteride, which is another DHT-blocking treatment, Sphinganine offers the benefits of topical use without the characteristic side effects associated with oral treatments. This makes it a safer alternative for those who are sensitive to systemic medications. Additionally, Sphinganine provides anti-microbial benefits, effectively reducing Malassezia furfur, which helps to decrease scalp oiliness and prevent dandruff.
Can Sphinganine improve overall scalp health as well as hair growth?
Yes, Sphinganine not only prevents hair loss and promotes hair growth but also improves scalp health. Its anti-microbial properties help reduce the presence of Malassezia furfur, balance the microflora, and reduce scalp oiliness. By addressing these issues, Sphinganine helps maintain a healthier scalp, which is essential for optimal hair appearance and growth.
Who is most likely to benefit from using Sphinganine?
Individuals experiencing androgenetic alopecia, especially men after puberty, are likely to benefit the most from using Sphinganine. Since it targets the underlying causes of hair thinning, such as high levels of DHT in the hair follicle and the miniaturization of hair follicles, Sphinganine can be an effective prevention method for those genetically predisposed to hair loss and seeking to improve their hair quality.
If you have any questions, please contact us. You will get a satisfactory answer.
