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Safflower Oil

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Catalog Number CI-SC-0516
Product Name Safflower Oil
CAS 8001-23-8
Synonyms Safflower oleosomes
Description Safflower oil is rich in essential fatty acids, primarily linoleic acid (C18:2) but is also high in oleic acid (C18:1). The Linoleic acid content of safflower oil is typically found at levels over 70%. Extraction method: Expeller pressed, refined. SAP Value: 186-198.
Density 0.921 g/mL
Solubility Oil-soluble
Appearance Clear honey-colored liquid
Application Skin care and hair products
Storage Store light-protected at a cool and dry place
HS Code 1518009000
INCI Carthamus Tinctorius (Safflower) oil
Uses Add to oil-phase of emulsions. Typical use level 1-20%. For external use only.
Product Overview

Safflower oil, extracted from the seeds of the Carthamus tinctorius plant, is renowned for its versatile applications in both the food and cosmetic industries. Rich in unsaturated fatty acids, particularly linoleic acid, this oil is highly valued for its excellent emollient properties, which allow it to penetrate the skin barrier effectively. With approximately 80% linoleic acid content, safflower oil plays a crucial role in maintaining healthy skin, offering moisturizing and anti-inflammatory benefits without causing irritation or aggravating acne. Its unique composition, with an exceptionally high level of mono-unsaturated fats similar to oleic acid, ensures remarkable stability, making it suitable for high-stability formulations. Additionally, its inclusion of vitamins A, D, K, and E supports skin defense, collagen production, and cellular metabolism, making it a favored ingredient in skincare products like creams, lotions, and lip balms. Despite its hydrophobic nature, which can present formulation challenges, safflower oil's non-masking flavor and ability to nourish and protect skin from free radicals significantly enhance its value as a natural anti-aging ingredient.

Case Study

Phenolic Ingredients, Antioxidant and Anti-Aging Activities of Safflower Oil

Zemour, Kamel, et al. Cosmetics, 2019, 6(3), 55.

This work evaluated the quantitative analysis of methanolic extractables (TPC) in safflower seed oil and its antioxidant and anti-aging activities. Safflower seed oil was found to be a great source of polyphenols, which have antioxidant and anti-aging activities.
The total phenolic content of safflower oil and its antioxidant activity are strongly affected by the genotype used and the growth conditions. Genotype, year (climate conditions) and their interaction significantly affected these traits.
The methanolic extract of safflower oil exhibited 20% antioxidant activity across all tested genotypes, and it was demonstrated a positive correlation between the total phenolic content and its antioxidant effectiveness.
The anti-aging activity of safflower oil was evaluated. The results showed that safflower oil inhibited the activity of collagenase and elastase, highlighting its potential as a source of natural anti-aging agents in cosmetic formulations. Inhibition rates in the collagenase assay varied from 47% to 72.1% compared to the positive control (83.1%), while the inhibition rates in the elastase assay for TPC ranged from 32.2% to 70.3% against the positive control (75.8%).
Moreover, notable anti-aging effects were observed across all genotypes examined.

Saponified Sunflower and Safflower Oils Inhibit Melanogenesis

Koo, Jeung-Hyun, et al. Molecular medicine reports, 2010, 3(2), 281-285.

In order to assess if saponified sunflower oil (sap-SU) and safflower oil (sap-SA) could be employed as skin-whitening agents, it was examined the extent to which these chemicals inhibited isobutylmethylxanthine (IBMX)-induced melanogenesis in B16 melanoma cells.
· Sunflower and safflower oil saponification.
SU or SA oil (1 g) was in ethanol, combined with 1 mL of 2.5 N KOH and saponified at 80 °C for 30 min. After saponification, the solution was pH regulated to 7.4.
· Potential process of sunflower and safflower oils.
Sap-SU and sap-SA oils demonstrated a dose-dependent inhibition of melanogenesis induced by isobutylmethylxanthine in B16 melanoma cells, without exhibiting cytotoxic effects. This slack in melanin production was associated with sluggish enzyme activity and lowered mRNA and protein levels of tyrosinase. Also, sap-SU and sap-SA caused reduced mRNA for microphthalmia-associated transcription factor and tyrosinase-related proteins 1 and 2, indicating that tyrosinase is regulated at the transcriptional level. All of these results suggest sap-SU and sap-SA as potential cosmetic whitening agents.

Custom Q&A

What is safflower oil, and how is it obtained?

Safflower oil is extracted from the seeds of the Carthamus tinctorius plant. It is an unsaturated oil characterized by its light texture and superb emollient properties. The oil quickly penetrates the skin barrier, providing excellent moisturization.

What are the primary benefits of using safflower oil in skincare?

Safflower oil is highly regarded in skincare due to its high linoleic acid content, which is about 80%. This acid plays a crucial role in maintaining healthy skin, repairing damaged skin, and providing moisturizing and anti-inflammatory benefits. The oil is suitable for all skin types and helps nourish, protect, and moisturize dry or dehydrated skin without irritating or aggravating acne.

What makes safflower oil unique compared to other oils?

Safflower oil has an exceptionally high mono-unsaturated level of about 90%, making it incredibly stable and surpassing other natural liquid oils in terms of stability. Its unique composition makes it well-suited for high-stability applications in the cosmetic industry. Furthermore, it contains essential vitamins such as A, D, K, and E, which contribute to maintaining skin defense, collagen production, and cellular metabolism.

How is safflower oil used in the cosmetic industry?

Due to its moisturizing properties, safflower oil is incorporated into various skincare formulations such as creams, lotions, and lip balms. However, incorporating the oil into formulas can be challenging because of its strong hydrophobic property. Nonetheless, its clean and non-masking flavor makes it advantageous for various processes within the industry.

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