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| Catalog Number | CI-BP-0078 |
| Product Name | Rhodamine B-5(or 6)-isothiocyanate |
| CAS | 100684-36-4 |
| Synonyms | Hexapeptide-11 |
| IUPAC Name | 3',6'-bis(diethylamino)-5-isothiocyanatospiro[2-benzofuran-3,9'-xanthene]-1-one |
| Molecular Weight | 499.6 g/mol |
| Molecular Formula | C29H29N3O3S |
| InChI | InChI=1S/C29H29N3O3S/c1-5-31(6-2)20-10-13-23-26(16-20)34-27-17-21(32(7-3)8-4)11-14-24(27)29(23)25-15-19(30-18-36)9-12-22(25)28(33)35-29/h9-17H,5-8H2,1-4H3 |
| InChI Key | OTFIRIMNKLNLIK-UHFFFAOYSA-N |
| Density | 1.235 g/mL |
| Appearance | Crystalline powder |
| Isomeric SMILES | CCN(CC)C1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)N(CC)CC)C5=C(C=CC(=C5)N=C=S)C(=O)O3 |
What is Rhodamine B-5(or 6)-isothiocyanate and what are its primary benefits in skincare?
Rhodamine B-5(or 6)-isothiocyanate, also known as Hexapeptide-11, is a synthetic cosmetic ingredient that is initially derived from yeast (Saccharomyces cerevisiae) and then synthesized for high purity. It is renowned for its anti-aging and hydrating benefits. It acts as a signaling peptide, composed of amino acids like alanine, phenylalanine, proline, and valine, which enhance the skin's elasticity, firmness, and hydration. Moreover, it provides antioxidant properties that protect the skin from environmental stressors, potentially improving skin health longevity.
In what forms is Hexapeptide-11 available, and what are the recommended usage levels?
Hexapeptide-11 is available either as a powder or in a liquid solution. When utilizing this ingredient in skincare formulations, suppliers advise maintaining usage levels between 0.001% and 0.01% to achieve optimal results.
How does Hexapeptide-11 contribute to anti-aging effects on the skin?
Hexapeptide-11 functions as a signaling peptide that impacts the skin's elasticity and firmness, which are essential for counteracting the signs of aging. It also offers antioxidant properties, aiding in the protection against environmental stressors, which can accelerate aging. There is also preliminary research suggesting that Hexapeptide-11 might improve the skin's healthspan by interacting with senescent cells, potentially supporting prolonged skin vitality and resilience.
What are the research and development insights on the effectiveness of Hexapeptide-11?
Research has demonstrated that Hexapeptide-11 positively influences skin elasticity and firmness while hydrating the skin. Preliminary studies are promising regarding its potential to improve the skin's longevity by interacting with senescent cells. The ongoing research may further unveil its benefits and expand the understanding of its role in enhancing skin health and appearance. We anticipate updating information as new research developments are published.
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