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| Catalog Number | CI-GU-0049 |
| Product Name | Retinyl Palmitate |
| CAS | 79-81-2 |
| Structure |  |
| Synonyms | Vitamin A palmitate, All-trans-retinyl palmitate |
| IUPAC Name | [(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] hexadecanoate |
| Molecular Weight | 524.86 g/mol |
| Molecular Formula | C36H60O2 |
| InChI | InChI=1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+ |
| InChI Key | VYGQUTWHTHXGQB-FFHKNEKCSA-N |
| Boiling Point | 546.5 °C |
| Melting Point | 28-29 °C |
| Flash Point | 194°C |
| Purity | 95% |
| Density | 0.97 g/mL |
| Appearance | Oil |
| Highest Usage In Residency Products | 0.05 |
| Isomeric SMILES | CCCCCCCCCCCCCCCC(=O)OC/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(CCCC1(C)C)C |
Retinyl Palmitate is a stable form of vitamin A commonly incorporated into skincare products for its skin-normalizing properties. As a precursor to retinoic acid, it is effective in promoting the youthful function of skin cells thereby nourishing the skin when applied topically. This compound is found in a range of skincare formulations, particularly those aimed at regeneration nourishment and post-sun care with typical concentrations ranging from 02% to 05%. Retinyl Palmitate is slightly soluble in alcohol miscible with oils and insoluble in water presenting as a clear golden oily liquid with a faint odor. In the presence of specific skin enzymes, it undergoes conversion to retinoic acid which actively contributes to reversing photoaging, enhancing collagen and elastin synthesis, and protecting cells against free radical-induced damage-a key factor in premature aging. Additionally, this compound supports skin health at a cellular level by penetrating deeply, due to its relatively small molecular size thus improving the overall condition of the skin.
What are the key benefits of using Retinyl Palmitate in skincare products?
Retinyl Palmitate, a derivative of Vitamin A, offers several skin benefits when appropriately formulated and used at the correct levels. It penetrates the skin effectively, providing anti-keratinization properties and increasing skin elasticity. Additionally, it helps in the thickening of both the epidermis and dermis, normalizes dry and dehydrated skin, and reverses photodamage. In hair care products, it reduces scaliness and normalizes the scalp.
Is Retinyl Palmitate a safe ingredient to use in cosmetics?
Yes, according to the Cosmetic Ingredient Review (CIR) expert panel, Retinyl Palmitate, as well as Retinol, is considered safe for use as a cosmetic ingredient under the current practices of use and concentration. This ensures that when used properly, it does not pose any safety concerns.
How does Retinyl Palmitate differ from other retinoids in terms of side effects?
Retinyl Palmitate is known to provide similar benefits to other retinoids but with fewer side effects. This makes it a preferable choice for those who seek the skin-enhancing benefits of retinoids but are concerned about the potential side effects associated with more potent forms.
Can Retinyl Palmitate be used to manage photodamage and improve skin texture?
Yes, Retinyl Palmitate is effective in reversing photodamage and improving skin texture. It thickens the skin layers and increases elasticity, which contributes to a more youthful and healthy skin appearance.
Is Retinyl Palmitate beneficial for hair care, and if so, how?
Retinyl Palmitate is beneficial in hair care products as it helps reduce scaliness and normalize the scalp. This can lead to healthier hair and scalp conditions, offering improvements in texture and overall scalp health.
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