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| Catalog Number | CI-OT-0026 |
| Product Name | Pyridoxine Dipalmitate |
| CAS | 635-38-1 |
| Structure |  |
| Synonyms | Palmitic acid, diester with 5-hydroxy-6-methylpyridine-3,4-dimethanol |
| IUPAC Name | [4-(hexadecanoyloxymethyl)-5-hydroxy-6-methylpyridin-3-yl]methyl hexadecanoate |
| Molecular Weight | 646 g/mol |
| Molecular Formula | C40H71NO5 |
| InChI | InChI=1S/C40H71NO5/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-38(42)45-33-36-32-41-35(3)40(44)37(36)34-46-39(43)31-29-27-25-23-21-19-17-15-13-11-9-7-5-2/h32,44H,4-31,33-34H2,1-3H3 |
| InChI Key | RCYWWJBNPIWJMJ-UHFFFAOYSA-N |
| Boiling Point | 716.9±55.0 °C |
| Melting Point | 87-91 °C |
| Purity | 95% |
| Density | 0.97 g/mL |
| Appearance | Solid |
| Highest Usage In Residency Products | 0.005 |
| Isomeric SMILES | CCCCCCCCCCCCCCCC(=O)OCC1=CN=C(C(=C1COC(=O)CCCCCCCCCCCCCCC)O)C |
| pKa | 8.97±0.10 |
Pyridoxine Dipalmitate, a derivative of Vitamin B6, is commonly employed as a functional additive in cosmetics due to its enhanced skin permeability and stability compared to the base vitamin. This white crystalline powder while odorless offers versatile solubility characteristics, being readily dissolved in oils slightly soluble in hot ethanol and insoluble in water. Its primary applications in creams, skincare emulsions and hair care products, are aimed at addressing various skin conditions including roughness acne and sunburn mitigation, as well as treating seborrheic trichomonosis skin inflammation and seborrheic eczema. Typically, incorporated at concentrations of 05% to 20%, it is often used in conjunction with other vitamins to maximize its efficacy in promoting healthier skin and hair.
What is Pyridoxine Dipalmitate and what are its main properties?
Pyridoxine Dipalmitate, also known as Vitamin B6 Dipalmitate, is a white or similar white crystal or crystalline powder that is odorless. It is notable for its ability to dissolve easily in oils, is slightly soluble in ethanol when heated, and cannot be dissolved in water. This derivative of Vitamin B6 is recognized for better skin permeation and enhanced stability compared to its original form.
What are the primary uses of Pyridoxine Dipalmitate in cosmetics?
Pyridoxine Dipalmitate is primarily used as a cosmetic functional additive. It is effective in preventing and treating various skin conditions such as roughness, acne, and sunburns. Additionally, it is used in the treatment of seborrheic trichomonosis, skin inflammation, general acne, and seborrheic eczema. Its versatile properties make it suitable for inclusion in creams, skincare emulsions, and hair care products.
How is Pyridoxine Dipalmitate typically incorporated into cosmetic formulations?
In cosmetic formulations, Pyridoxine Dipalmitate is typically combined with other vitamins. It is used at a concentration level ranging from 0.5% to 2.0%, depending on the specific application and desired efficacy in the final product.
What are the solubility characteristics of Pyridoxine Dipalmitate?
Pyridoxine Dipalmitate is easily dissolved in oil, offering a versatile option for oil-based formulations. It is slightly soluble in ethanol when warmed, allowing for varied solubility depending on the preparation method. However, it does not dissolve in water, which should be considered when formulating water-based products.
Are there particular skin or hair conditions that benefit most from the use of Pyridoxine Dipalmitate?
Yes, Pyridoxine Dipalmitate is particularly beneficial for addressing skin roughness, acne, and sunburns. It is also used effectively in the treatment of seborrheic trichomonosis, skin inflammation, general acne, and seborrheic eczema, making it a valuable ingredient in tailored skincare regimes and hair care treatments.
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