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Propylene Glycol

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Catalog Number CI-SC-0001
Product Name Propylene Glycol
CAS 57-55-6
Structure
Synonyms Propyleneglycol manufacturer
Description Modified alcohol (1,2-propanediol), metabolized to lactic acid in the body.
IUPAC Name Propane-1,2-diol
Molecular Weight 76.09 g/mol
Molecular Formula C3H8O2
Canonical SMILES CC(CO)O
InChI InChI=1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
InChI Key DNIAPMSPPWPWGF-UHFFFAOYSA-N
Boiling Point 187 °C(lit.)
Melting Point -60 °C(lit.)
Flash Point 225 °F
Purity 99+%
Density 1.036 g/mL at 25 °C(lit.)
Solubility Soluble in water, ethanol, acetone
Appearance Liquid
Application All kinds of skin care products, hair care products, color cosmetics, soaps (glycerin soap).
Storage 5-30 °C
Composition Propylene glycol
Features And Benefits Effective humectant and wetting agent preventing water loss in products and in the skinIncreases skin permeability of active ingredients as it penetrates into the outermost skin layersEmollient and lubricant propertiesExcellent solubilizer of other ingredientsIncreases spreading of creams
GMO GMO-free (does not contain plant-derived components)
HS Code 2905320000
INCI Propylene glycol
Manufacture Non-catalytic hydrolysis of propylene oxide to form a mixture of mono-, di-, and tripropylene glycols
Preservation Preservative-free
Purity Grade No purity grade applicable
Raw Material Source Propylene oxide (made from propylene and hydrogen peroxide)
Refractive Index n20/D 1.432(lit.)
Topological Polar Surface Area 40.5 Ų
Uses Add as is to the water phase of the formulas, typical use level 1-8% in emulsions. For external use only.
Custom Q&A

What is the molecular formula of propylene glycol?

The molecular formula of propylene glycol is C3H8O2.

What are the physical and chemical properties of propylene glycol?

The physical and chemical properties of propylene glycol include a boiling point of 187°C, a density of 1.036 g/mL at 25°C, and a vapor pressure of 0.08 mm Hg at 20°C.

How is propylene glycol used in the medicinal field?

Propylene glycol is used as a solvent, extraction solvent, and preservative for pharmaceutical preparations such as injections, oral liquids, and ophthalmic preparations.

What are some products that propylene glycol is used in?

Propylene glycol is used in unsaturated polyester, epoxy resin, polyurethane resin, food, pharmaceuticals, cosmetics, and as a solvent in flavorings and pigments.

What is the synthesis method of propylene glycol?

Propylene glycol can be obtained through the hydrolysis of propylene oxide or through direct hydration methods with water and propylene oxide.

What is the acute toxicity of propylene glycol?

The oral LD50 for rats is 20000 mg/kg and for mice is 32000 mg/kg.

What is the use limitation of propylene glycol according to the FDA?

The FDA has specified use limitations for propylene glycol in various food products, ranging from 2% to 97% depending on the type of food.

What are some safety measures to take when using propylene glycol?

Safety statements recommend storing propylene glycol at temperatures of +5°C to +30°C and applying dry powder, foam, sand, or water as extinguishing agents.

How does propylene glycol compare to other glycols in terms of usage?

Propylene glycol is used for similar applications as other glycols but has advantages such as being non-toxic, viscous, and stable at low temperatures.

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