Our customer service representatives are available 24 hours a day, from Monday to Sunday.
| Catalog Number | CI-SC-0215 |
| Product Name | Polysorbate 80 |
| CAS | 9005-65-6 |
| Synonyms | Tween 80 |
| Description | Emulsifying agent consisting of sorbitol, ethylene oxide & oleic acid (polyoxyethylene-80 sorbitan monooleate), oleic acid is derived from vegetable oil. Purity > 95%. Saponification value 45-55. HLB value 15 (gives oil-in-water emulsions). |
| IUPAC Name | 2-[2-[3,4-Bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl octadec-9-enoate |
| Molecular Weight | 604.8 g/mol |
| Molecular Formula | C32H60O10 |
| Canonical SMILES | CCCCCCCCC=CCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO |
| InChI | InChI=1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-26-28(38-21-18-33)32-31(41-23-20-35)29(27-42-32)39-22-19-34/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+ |
| InChI Key | HDTIFOGXOGLRCB-MDZDMXLPSA-N |
| Melting Point | -21°C |
| Flash Point | >110°C |
| Purity | 99%+ |
| Density | 1.064 g/mL |
| Solubility | Soluble in water & alcohols, insoluble in oils |
| Appearance | Amber, viscous liquid, odorless |
| Application | Body washes, hair shampoos, hair loss treatments, lotions, creams, bath oils, solubilizates. |
| Storage | Store in a closed container at a dry place at room temperature |
| Composition | Polysorbate-80 |
| Features And Benefits | Non-ionic, multi-purpose emulsifier (enables water and oil to mix)Emulsifying efficacy is increased when combined with cetyl alcohol or sorbitan stearateActs as dispersing agent and anti-static thickenerVery useful as solubilizer and stabilizer of essential oilsMay be useful as hair growth supplement |
| GMO | GMONo data available |
| HS Code | 3402130000 |
| INCI | Polysorbate-80 |
| Isomeric SMILES | CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO |
| Manufacture | Polysorbate 80 is obtained by esterification of sorbitol with one or three molecules of a fatty acid including stearic, lauric, oleic, and palmitic acid. |
| Preservation | Preservative-free |
| Purity Grade | No purity grade applicable |
| Raw Material Source | Sorbitol, vegetable oils |
| Refractive Index | 1.471-1.473 |
| Topological Polar Surface Area | 133 Ų |
| Uses | Can be added to formulas as is. Typical use level is 1 - 10%. For external use only. |
Polysorbate 80, a polyethoxylated sorbitan ester, is highly regarded for its efficacy as an oil-in-water emulsifier, characterized by its amber, viscous, and odorless liquid form. With an HLB value of 15.0, it dissolves readily in both water and alcohol, making it versatile for use in various formulations, including both oil-in-water and water-in-oil systems. It is particularly effective in combination with sorbitan monostearates and is compatible with unsaturated lipid components such as oleyl alcohol and vegetable triglycerides. Polysorbate 80 enhances fragrance or emollient solubilization and serves as a reliable emulsifier in applications like skincare emulsions, makeup foundations, and hair rinses. By pairing with low HLB emulsifiers and fatty alcohols, such as cetearyl alcohol, it helps in creating stable emulsions. Frequently combined with Sorbitan Oleate, Polysorbate 80 can also function as a stabilizer, wetting, and dispersing agent. This multifunctional ingredient is suitable for skin care, oral, parenteral, and ophthalmic preparations and can be found in products like body washes, shampoos, lotions, creams, bath oils, and solubilizates, typically within a 1-5% concentration range. It is recognized as a safe component in Active Pharmaceutical Ingredient production, a multipurpose food additive, and as a filler in vitamin-mineral supplements.
What is Polysorbate 80 and how is it used in cosmetic formulations?
Polysorbate 80 is a polyethoxylated sorbitan ester, specifically a 20-mole ethoxylate of sorbitan monooleate, which serves as an outstanding oil-in-water emulsifier with a high HLB value of 15.0. In cosmetic formulations, it is utilized for its ability to emulsify and stabilize products. Its applications include use in skin care emulsions, make-up foundations, and hair rinses due to its solubilization capabilities for fragrances, emollients, and its function as a wetting agent.
In what types of products can Polysorbate 80 be found?
Polysorbate 80 is found in a wide range of personal care and cosmetic products such as body washes, hair shampoos, lotions, creams, and bath oils. Its versatility and safety also allow it to be used in oral, parenteral, and ophthalmic preparations as well as food additives and vitamin-mineral supplements.
How does Polysorbate 80 interact with other emulsifiers?
Polysorbate 80 can effectively be combined with low-HLB emulsifiers to create stable emulsions, particularly when paired with fatty alcohols like Cetearyl alcohol. This combination is ideal for forming stable systems, and a renowned emulsifier blend is Polysorbate 80 with Sorbitan Oleate. It is especially useful in systems containing unsaturated lipid components like oleyl alcohol and vegetable triglycerides.
What is the typical concentration of Polysorbate 80 used in formulations?
Polysorbate 80 is typically used at a concentration ranging from 1% to 5% in formulations. This range provides optimal functionality in terms of emulsification, stabilization, and solubilization in various products.
Is Polysorbate 80 considered safe for various applications?
Yes, Polysorbate 80 is considered a safe ingredient across multiple industries. It is recognized as a multi-purpose food additive under 21CFR 172.846 and is also used as a filler in vitamin-mineral supplements as cited in 21CFR 172.840. Its safety and efficacy extend to its application in Active Pharmaceutical Ingredient (API) production.
If you have any questions, please contact us. You will get a satisfactory answer.
