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| Catalog Number | CI-SC-0215 |
| Product Name | Polysorbate 80 |
| CAS | 9005-65-6 |
| Synonyms | Tween 80 |
| Description | Emulsifying agent consisting of sorbitol, ethylene oxide & oleic acid (polyoxyethylene-80 sorbitan monooleate), oleic acid is derived from vegetable oil. Purity > 95%. Saponification value 45-55. HLB value 15 (gives oil-in-water emulsions). |
| IUPAC Name | 2-[2-[3,4-Bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl octadec-9-enoate |
| Molecular Weight | 604.8 g/mol |
| Molecular Formula | C32H60O10 |
| Canonical SMILES | CCCCCCCCC=CCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO |
| InChI | InChI=1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-26-28(38-21-18-33)32-31(41-23-20-35)29(27-42-32)39-22-19-34/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+ |
| InChI Key | HDTIFOGXOGLRCB-MDZDMXLPSA-N |
| Melting Point | -21°C |
| Flash Point | >110°C |
| Purity | 99%+ |
| Density | 1.064 g/mL |
| Solubility | Soluble in water & alcohols, insoluble in oils |
| Appearance | Amber, viscous liquid, odorless |
| Application | Body washes, hair shampoos, hair loss treatments, lotions, creams, bath oils, solubilizates. |
| Storage | Store in a closed container at a dry place at room temperature |
| Composition | Polysorbate-80 |
| Features And Benefits | Non-ionic, multi-purpose emulsifier (enables water and oil to mix)Emulsifying efficacy is increased when combined with cetyl alcohol or sorbitan stearateActs as dispersing agent and anti-static thickenerVery useful as solubilizer and stabilizer of essential oilsMay be useful as hair growth supplement |
| GMO | GMONo data available |
| HS Code | 3402130000 |
| INCI | Polysorbate-80 |
| Isomeric SMILES | CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO |
| Manufacture | Polysorbate 80 is obtained by esterification of sorbitol with one or three molecules of a fatty acid including stearic, lauric, oleic, and palmitic acid. |
| Preservation | Preservative-free |
| Purity Grade | No purity grade applicable |
| Raw Material Source | Sorbitol, vegetable oils |
| Refractive Index | 1.471-1.473 |
| Topological Polar Surface Area | 133 Ų |
| Uses | Can be added to formulas as is. Typical use level is 1 - 10%. For external use only. |
What is the chemical formula of Tween 80?
The chemical formula of Tween 80 is C24H44O6.
What are the synonyms of Tween 80?
Some of the synonyms of Tween 80 include armotanpmo-20, atlox1087, and atlox8916tf.
What are some common uses of Polysorbate 80?
Tween 80 is commonly used as a defoamer in wine fermentation, as an emulsifier in ice cream, and as a surfactant in soaps and cosmetics.
At what temperature does Tween 80 have a boiling point greater than?
Tween 80 has a boiling point greater than 100°C.
What is the odor of Tween 80 described as?
The odor of Tween 80 is described as mild alcoholic.
What is the pH range of Tween 80 in a 50g/l aqueous solution at 20°C?
The pH range of Tween 80 is 5-7 in a 50g/l aqueous solution at 20°C.
What are some safety hazards associated with Tween 80?
Some safety hazards associated with Tween 80 include risk statements 22-41, toxicity in mice and rats, and potential reproductive effects.
What are some properties of Tween 80 as a surfactant?
Tween 80 is a viscous liquid with a warm, somewhat bitter taste, and it is a nonionic surfactant widely used in biochemical applications.
How is Tween 80 used in pharmaceuticals?
Tween 80 is commonly used in pharmaceuticals as an excipient to stabilize aqueous formulations of medications for parenteral administration.
What are some biological effects of Tween 80?
Tween 80 is used as an additive in cell culture media and has been shown to increase the transformation frequency of certain bacteria.
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