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| Catalog Number | CI-BP-0091 |
| Product Name | Pentapeptide-1 |
| CAS | 69558-55-0 |
| Structure |  |
| Synonyms | Thymopoietin pentapeptide |
| Molecular Weight | 679.77 g/mol |
| Molecular Formula | C30H49N9O9 |
| Purity | 0.95 |
| Density | 1.44 g/mL |
| Appearance | White powder |
| Storage | -15~-20 °C |
| pKa | 3.07±0.10 |
| Safety | No heavy metals, no skin and eye irritation |
Pentapeptide-1 is a synthetic recombinant peptide developed from thymopoietin, a human hormone known for its immunomodulating properties. Its sequence, Arg-Lys-Asp-Val-Tyr, corresponds to a specific active segment of the protein's amino acid chain. Pentapeptide-1, also marketed as Sintomodulina, is widely used in the topical treatment of atopic dermatitis, contact dermatitis, and chronic skin infections. When incorporated into skincare formulations, it has demonstrated significant potential for soothing sensitive skin and combating irritations effectively.
What is Pentapeptide-1, and how does it work?
Pentapeptide-1, also known as sh-Pentapeptide-1, is a synthetic recombinant peptide derived from thymopoietin, a hormone with immunomodulating properties. Its specific amino acid sequence is Arg-Lys-Asp-Val-Tyr, corresponding to the active region of the thymopoietin protein. This peptide is recognized for its potential in enhancing skin health by modulating immune responses.
What are the primary uses of Pentapeptide-1 in skincare?
Pentapeptide-1 is primarily used in skincare for the topical treatment of atopic dermatitis, contact dermatitis, and chronic skin infections. It's known for its ability to soothe sensitive skin and effectively reduce irritation, making it a valuable component in skincare formulations targeting these conditions.
How is Pentapeptide-1 applied in dermatological care?
Pentapeptide-1 is incorporated into various skincare preparations and topical treatments. When applied to the skin, it works by interacting with the local immune response, helping to manage conditions associated with inflammation and irritation, such as dermatitis.
Is Pentapeptide-1 suitable for all skin types?
Pentapeptide-1 is particularly beneficial for individuals with sensitive skin or those prone to irritations. However, as with any skincare ingredient, it's recommended to perform a patch test or consult with a dermatologist to ensure compatibility with your specific skin type.
What makes Pentapeptide-1 unique?
Its uniqueness stems from its ability to mimic a segment of thymopoietin, a human hormone, allowing it to modulate immune responses at the skin level effectively. This makes it a promising ingredient in treatments for various skin conditions characterized by inflammation.
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