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| Catalog Number | CI-SC-0055 |
| Product Name | Palmitoyl Tripeptide-1 |
| CAS | 147732-56-7 |
| Structure |  |
| Synonyms | L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl- |
| Description | Palmitoyl Tripeptide-1 is a synthetic peptide that is often used in skincare products as an anti-aging agent. It is a combination of three amino acids - glycine, histidine, and lysine, along with a lipid called palmitic acid. The compound is designed to mimic the body's own peptides that are responsible for collagen production. Palmitoyl Tripeptide-1 works by stimulating collagen synthesis, which is essential for maintaining skin elasticity and firmness. It also helps to smooth out fine lines and wrinkles, giving the skin a more youthful appearance. Additionally, this compound can boost the production of hyaluronic acid, which helps to keep the skin hydrated and plump. |
| Molecular Weight | 578.79 g/mol |
| Molecular Formula | C30H54N6O5 |
| Appearance | white to off-white powder |
| Application | 1. Stimulates collagen production - Palmitoyl Tripeptide-1 has been found to stimulate the production of collagen, a vital structural protein that is responsible for keeping the skin firm and elastic. 2. Reduces the appearance of fine lines and wrinkles - By boosting collagen production, Palmitoyl Tripeptide-1 helps to improve the elasticity and firmness of the skin. This can help to reduce the appearance of fine lines and wrinkles. 3. Improves skin texture and tone - Palmitoyl Tripeptide-1 has been shown to improve the overall texture and tone of the skin, making it look brighter, smoother, and more youthful. 4. Improves skin hydration - Palmitoyl Tripeptide-1 has been found to help improve the skin's moisture retention, which can help to keep it hydrated and supple. 5. Reduces inflammation - Palmitoyl Tripeptide-1 has anti-inflammatory properties, which can help to reduce redness, irritation, and swelling in the skin. 6. Increases skin thickness - Palmitoyl Tripeptide-1 has been shown to increase the thickness of the epidermis, the outermost layer of the skin. Thicker skin can help to reduce the appearance of fine lines and wrinkles, and can also protect the skin from environmental damage. 7. Enhances wound healing - Palmitoyl Tripeptide-1 has been found to enhance the process of wound healing, making it an effective ingredient in products that target skin repair and rejuvenation. |
| Features And Benefits | 1. Stimulates collagen production 2. Improves skin elasticity 3. Reduces the appearance of fine lines and wrinkles 4. Helps to hydrate and moisturize the skin 5. Promotes wound healing 6. Prevents inflammation and irritation of the skin 7. Enhances skin's firmness and smoothness 8. Improves overall skin tone and texture. |
Palmitoyl Tripeptide-1, a derivative of the well-researched Tripeptide-1, plays a pivotal role in modern skincare, taking advantage of its unique ability to enhance skin's structure and appearance. As a modified peptide with a fatty acyl group connected to its N-terminus, Palmitoyl Tripeptide-1 has increased lipophilicity, allowing it to effectively penetrate the skin's lipid barrier and improve the delivery and performance of its active components. It promotes the activation of fibroblasts to increase the production of collagen and glycosaminoglycans, thereby smoothing fine lines and wrinkles and enhancing skin elasticity. This peptide is widely utilized in luxury skincare ranges under the trade name Biopeptide CL™ and in well-known complexes like Matrixyl™ 3000. Having undergone extensive safety tests, Palmitoyl Tripeptide-1 is safe for use in diverse applications, including sensitive areas such as the lips and eyes, due to its low irritation profile. Its ability to mimic growth factors allows it to bind to receptors on skin fibroblasts, signaling an increase in extracellular matrix production, which can help reveal a more youthful skin appearance.
What is Palmitoyl Tripeptide-1 and how does it work in skincare?
Palmitoyl Tripeptide-1, also known as Pal-GHK, is a modified form of the well-studied Tripeptide-1 (GHK peptide) with a palmitoyl group that enhances its lipophilicity. This allows it to penetrate the skin's lipid barrier effectively, boosting its delivery and effectiveness. It mimics the action of a natural growth factor by stimulating the production of collagen, hyaluronic acid, and glycosaminoglycans (GAGs), helping to smooth fine lines and wrinkles and improve skin elasticity.
How is Palmitoyl Tripeptide-1 used in cosmetic products?
Palmitoyl Tripeptide-1 is widely used in high-end skincare products for its anti-aging benefits. It is suitable for products targeting the sensitive areas around the eyes and lips, providing lifting and plumping effects while enhancing facial contours.
Is Palmitoyl Tripeptide-1 safe for use in skincare?
Yes, Palmitoyl Tripeptide-1 has undergone extensive safety testing, including toxicology assessments and clinical trials, which have demonstrated its non-irritating profile and efficacy in improving skin conditions. Its low irritation potential makes it suitable for use in products designed for sensitive areas like the eyes and lips.
What are the benefits of using Palmitoyl Tripeptide-1 in anti-aging formulations?
The primary benefits of Palmitoyl Tripeptide-1 include stimulating collagen and GAG production, smoothing fine lines and wrinkles, and enhancing skin elasticity and water-binding capacity. These effects help reveal a youthful, smoother, and healthier skin appearance, similar to the effects of retinoids, with which it can be combined to potentiate results.
Can Palmitoyl Tripeptide-1 be used with other active ingredients?
Yes, Palmitoyl Tripeptide-1 can be combined with other active ingredients such as retinoids to enhance their efficacy. It acts by mimicking the human transforming growth factor, binding to receptors on skin fibroblasts, and activating the production of extracellular matrix components, making it a versatile component in anti-aging skincare formulations.
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