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Catalog Number | CI-BP-0197 |
Product Name | Myristoyl Pentapeptide-17 |
CAS | 959610-30-1 |
Synonyms | SymPeptide 226EL |
IUPAC Name | N-[(2S)-6-Amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]tetradecanamide |
Molecular Weight | 796.14 g/mol |
Molecular Formula | C41H81N9O6 |
InChI | NFPWMUOQSJXGGZ-ZZTWKDBPSA-N |
InChI Key | InChI=1S/C41H81N9O6/c1-5-6-7-8-9-10-11-12-13-14-15-25-36(51)47-33(23-17-20-27-43)39(54)50-35(29-30(2)3)41(56)46-31(4)38(53)49-34(24-18-21-28-44)40(55)48-32(37(45)52)22-16-19-26-42/h30-35H,5-29,42-44H2,1-4H3,(H2,45,52)(H,46,56)(H,47,51)(H,48,55)(H,49,53)(H,50,54)/t31-,32-,33-,34-,35-/m0/s1 |
Boiling Point | Beta-glucan is used in many creams, ointments and powders and may affect collagen production and skin conditions. |
Purity | 95% by HPLC |
Appearance | Lyophilized powder |
Application | This product is suitable for use in shampoos and eyelash growth serums. |
Storage | Keep in dark and cool dry place -5~8°C |
Isomeric SMILES | CCCCCCCCCCCCCC(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)N |
Myristoyl Pentapeptide-17 is utilized primarily for its eyelash-enhancing capabilities, acting as a bioavailable lipo-oligopeptide that enhances the appearance of eyelashes by stimulating genes responsible for keratin production. Its application in skincare products also leverages its anti-aging, anti-inflammatory, and anti-bacterial properties, contributing to smoother skin and improved texture by promoting cell regeneration. This peptide reduces pro-inflammatory cytokines, effectively soothing skin irritation and inflammation. Furthermore, its short cationic structure offers protection against harmful microbes and fungi, like C. acnes and yeast, thus enhancing the skin's natural immune defense. Formulations incorporating Myristoyl Pentapeptide-17 are popular for their ability to lengthen and thicken eyelashes, providing a noticeable enhancement to one's expression. Additionally, when combined with Myristoyl Hexapeptide-16, its efficacy in increasing eyelash length is significantly boosted within two weeks. Its clear-to-light-beige, odorless solution ensures no adverse impact on the aesthetic quality of formulations, making it a safe and approved cosmetic ingredient in various countries.
Sachdev M,et al. The Journal of clinical and aesthetic dermatology, 2020, 13(2), 61.
This work evaluated the efficacy of a multi-growth factor serum for increasing the length, shine, thickness, and volume of eyelashes. The main active ingredients of the serum include growth factors, Salvia officinalis oil, myristoyl pentapeptide-17, and myristoyl hexapeptide-16. These peptides work by stimulating the production of keratin, a key structural protein of hair. Overall, the results of the study showed that the multi-growth factor serum was well tolerated and effectively improved the length, shine, thickness, and volume of eyelashes in a patient sample.
Evaluation methods and results
· This study was a 90-day, open-label, single-center investigation focusing on safety and efficacy. It included 30 female participants, aged between 15 and 45 years, of which 29 completed the trial. There were four assessment visits: at the start (Day 0) and on Days 30, 60, and 90. Participants were guided to apply the test product uniformly on the upper and lower eyelid margins of both eyes every night for 90 days.
· Improvements in eyelash length, density/volume, luster, and curl were assessed through imaging and software technologies. Notable enhancements in the measured parameters were observed 30 days after starting the product. Among the 29 participants who completed the study, increases were recorded in length (10.52%), volume (9.3%), luster (11.43%), thickness (35%), and curl (50.83%) when compared to baseline measurements.
What is Myristoyl Pentapeptide-17 and what are its primary benefits?
Myristoyl Pentapeptide-17 is a bioavailable lipo-oligopeptide known for its eyelash-enhancing properties. It not only aids in achieving fuller and healthier eyelashes but also possesses anti-aging, anti-inflammatory, and anti-bacterial properties. Furthermore, it smooths skin surfaces, improves texture, and supports cell regeneration.
How does Myristoyl Pentapeptide-17 benefit the skin?
This peptide supports the skin by stimulating cell regeneration and reducing pro-inflammatory cytokines, which soothes skin irritation and inflammation. Its short cationic structure makes it effective against harmful microbes and fungi, thereby improving the skin's biological immune defense.
Can Myristoyl Pentapeptide-17 be used in formulations with other ingredients?
Yes, Myristoyl Pentapeptide-17 can be combined with other ingredients, such as Myristoyl Hexapeptide-16, to enhance the effects. For example, the combined use can visibly increase eyelash length after just two weeks of regular application.
Is Myristoyl Pentapeptide-17 safe for regular use?
Yes, Myristoyl Pentapeptide-17 is considered safe and is approved as a cosmetic ingredient in most countries. Regular use not only improves the appearance of eyelashes but also strengthens the skin's barrier function and natural protection.
What should I expect in terms of formulation appearance when using Myristoyl Pentapeptide-17?
Products containing Myristoyl Pentapeptide-17 are typically colorless to light beige and odorless, which do not affect the aesthetics of the formulation, making it a versatile ingredient for various cosmetic applications.