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| Catalog Number | CI-BP-0076 |
| Product Name | Myristoyl hexapeptide-4 |
| CAS | 959610-44-7 |
| Synonyms | L-Lysinamide, N-(1-oxotetradecyl)-L-seryl-L-threonyl-L-lysyl-L-threonyl-L-threonyl- |
| Molecular Weight | 874.12 g/mol |
| Molecular Formula | C41H79N9O11 |
| Boiling Point | 1243.9±65.0 °C |
| Purity | 0.95 |
| Density | 1.177 g/mL |
| Appearance | White powder |
| Storage | -15~-20 °C |
| pKa | 13.20±0.46 |
| Safety | No heavy metals, no skin and eye irritation |
Myristoyl Hexapeptide-4 is a hydrophilic peptide known for its bioactive properties, primarily due to its rich composition of the essential amino acid threonine in the sequence Myr-Thr-Lys-Thr-Thr-Lys-Ser-NH2. This advanced peptide enhances the production of structural proteins in the skin while inhibiting the MMP-1 enzyme, which plays a role in collagen breakdown. In vitro studies have demonstrated that Myristoyl Hexapeptide-4 effectively upregulates genes associated with the synthesis of collagen IV and VII, as well as fibronectin, elastin, and integrin, while simultaneously downregulating genes linked to MMP-1 production. The result is a significant prevention of collagen degradation, leading to firmer, smoother skin with improved elasticity. Additionally, this peptide aids in boosting skin hydration and maintaining an optimal balance, promoting an overall healthier appearance.
What is Myristoyl Hexapeptide-4, and what are its primary functions?
Myristoyl Hexapeptide-4 is a hydrophilic peptide that is rich in the essential amino acid threonine. Its sequence is Myr-Thr-Lys-Thr-Thr-Lys-Ser-NH2. Due to modifications during production, it is more bioactive, which enhances its effectiveness. The peptide's primary functions include boosting the production of the skin's structural proteins and inhibiting the synthesis of the MMP-1 enzyme, which is responsible for collagen destruction.
How does Myristoyl Hexapeptide-4 benefit the skin's structural integrity?
Myristoyl Hexapeptide-4 benefits the skin's structural integrity by upregulating genes responsible for synthesizing collagen IV and VII, fibronectin, elastin, and integrin. This process not only enhances the production of crucial proteins for maintaining skin structure but also helps to downregulate genes that produce MMP-1, an enzyme that contributes to collagen degradation. This dual action helps in making the skin firmer and improving its elasticity.
What additional benefits does Myristoyl Hexapeptide-4 provide for the skin?
In addition to improving structural integrity, Myristoyl Hexapeptide-4 makes the skin smoother and improves its elasticity. It also promotes skin hydration, helping to maintain a healthy balance. These benefits together contribute to a more youthful and healthier-looking skin appearance.
Has Myristoyl Hexapeptide-4 been evaluated in studies for its effectiveness?
Yes, in vitro studies have shown that Myristoyl Hexapeptide-4 effectively upregulates the genes necessary for collagen and protein synthesis. In addition, it downregulates the genes responsible for MMP-1 production, preventing collagen degradation and enhancing its quantities within the skin, thus confirming its effectiveness in promoting skin health and appearance.
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