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| Catalog Number | CI-SC-1320 |
| Product Name | Magnesium Ascorbyl Phosphate |
| CAS | 113170-55-1 |
| Structure |  |
| Synonyms | Ascorbic acid, monoester with phosphoric acid, magnesium salt (2:3) |
| IUPAC Name | magnesium;[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2H-furan-4-yl] phosphate |
| Molecular Weight | 278.39 g/mol |
| Molecular Formula | C12H10Mg3O18P2-2 |
| InChI | InChI=1S/C6H9O9P.Mg/c7-1-2(8)4-3(9)5(6(10)14-4)15-16(11,12)13;/h2,4,7-9H,1H2,(H2,11,12,13);/q;+2/p-2/t2-,4+;/m0./s1 |
| InChI Key | ACFGRWJEQJVZTM-LEJBHHMKSA-L |
| Purity | 90% |
| Density | 1.74 g/mL |
| Appearance | Solid |
| Isomeric SMILES | C([C@@H]([C@@H]1C(=C(C(=O)O1)OP(=O)([O-])[O-])O)O)O.[Mg+2] |
Magnesium Ascorbyl Phosphate (MAP), an esterified derivative of Vitamin C, serves as a stable and powerful antioxidant utilized primarily in skincare formulations. Unlike traditional L-ascorbic acid, which is water-soluble and unstable, MAP is both lipophilic and water-soluble maintaining its stability at neutral pH and facilitating easy absorption through the skin. This characteristic allows MAP to deliver vitamin C effectively, as it is readily hydrolyzed into L-ascorbic acid and inorganic phosphate by the acidic phosphatases naturally present in human skin. Renowned for its ability to protect against photoaging UV-induced immunosuppression and potential cancer formation, MAP enhances collagen synthesis stabilizes collagen fibers and reduces their degradation. It also functions as a lightening agent by inhibiting tyrosinase, thereby diminishing melanin production and addressing uneven skin tone and hyperpigmentation. As a safe and non-irritating ingredient, MAP has been shown to promote hair growth particularly when combined with MSM, and stands out among other vitamin C derivatives for not destabilizing formulations, thus securing its place in high-end skincare products.
What is Magnesium Ascorbyl Phosphate (MAP)?
Magnesium Ascorbyl Phosphate (MAP) is an esterified derivative of Vitamin C, specifically the L-ascorbic acid 3-phosphate magnesium salt. It appears as a white or pale yellow powder, which is water-soluble and slightly soluble in ethanol. Unlike L-ascorbic acid, MAP is stable at a neutral pH and can be readily absorbed through the skin, making it a beneficial ingredient in skincare products.
How does Magnesium Ascorbyl Phosphate benefit the skin?
MAP is a potent antioxidant that offers several benefits for the skin. It protects against photoaging and UV-induced damage, supports collagen synthesis and stabilization, and decreases collagen destruction. Additionally, it reduces melanin synthesis, serving as an effective lightening and brightening agent for uneven skin tone or hyperpigmentation, such as age spots.
Is Magnesium Ascorbyl Phosphate stable in skincare formulations?
Yes, Magnesium Ascorbyl Phosphate is stable at a neutral pH and does not destabilize formulations, unlike some other Vitamin C derivatives. It is durable against hydrolysis in neutral or alkaline solutions, making it an ideal ingredient for high-end skincare products.
Can Magnesium Ascorbyl Phosphate cause irritation or toxicity?
Magnesium Ascorbyl Phosphate is considered to be a very safe ingredient with no known toxicity and low irritation potential. Its stability and gentle nature make it suitable for a wide range of skin types.
Does Magnesium Ascorbyl Phosphate provide any additional benefits beyond skin brightening and anti-aging?
In addition to its skin benefits, recent studies suggest that Magnesium Ascorbyl Phosphate may promote hair growth, particularly when used in conjunction with MSM (methylsulfonylmethane). This additional benefit extends its potential use in hair care products.
How does Magnesium Ascorbyl Phosphate compare to other Vitamin C derivatives?
Compared to other Vitamin C derivatives like ascorbyl palmitate or stearate, Magnesium Ascorbyl Phosphate offers stability without destabilizing formulations. It can be easily absorbed through the skin and is hydrolyzed in the skin to release L-ascorbic acid, making it an effective and versatile choice for cosmetic applications.
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