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Hexapeptide-3

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Catalog Number	CI-BP-0095
Product Name	Hexapeptide-3
CAS	1205679-02-2
Structure
Synonyms	L-Argininamide, L-α-glutamyl-L-α-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-
IUPAC Name	(4S)-4-amino-5-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
Molecular Weight	846.96 g/mol
Molecular Formula	C32H58N14O11S
InChI	InChI=1S/C32H58N14O11S/c1-58-15-12-21(46-29(56)20(8-11-24(50)51)43-26(53)16(33)6-10-23(48)49)30(57)45-19(7-9-22(34)47)28(55)44-18(5-3-14-41-32(38)39)27(54)42-17(25(35)52)4-2-13-40-31(36)37/h16-21H,2-15,33H2,1H3,(H2,34,47)(H2,35,52)(H,42,54)(H,43,53)(H,44,55)(H,45,57)(H,46,56)(H,48,49)(H,50,51)(H4,36,37,40)(H4,38,39,41)/t16-,17-,18-,19-,20-,21-/m0/s1
InChI Key	RYBWAQANBURYGX-PXQJOHHUSA-N
Purity	0.95
Density	1.56 g/mL
Appearance	White powder
Storage	-15~-20 °C
Isomeric SMILES	CSCC[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)N
pKa	4.24±0.10
Safety	No heavy metals, no skin and eye irritation

Product Overview

Hexapeptide-3, a synthetic biomimetic peptide with the sequence Ala-Asp-Leu-Lys-Pro-Thr, is utilized for its ability to emulate fibronectin found in the skin's extracellular matrix. This compound plays a crucial role in facilitating tissue repair, wound healing, and cell adhesion. By replicating essential functions of fibronectin, Hexapeptide-3 assists in enhancing cell adhesion and the organization of skin tissue, thereby promoting a youthful and healthy appearance. It stimulates the production of extracellular matrix proteins and strengthens the connection between dermal cells, contributing to a noticeable anti-aging effect and improved skin aesthetics. Additionally, Hexapeptide-3 boosts the expression of genes involved in integrin synthesis, further supporting skin repair mechanisms. Widely incorporated into skincare formulas, this peptide not only enhances skin smoothness and hydration but also provides significant plumping and rejuvenating effects on the lips, making it a popular choice in high-end lip care products.

Custom Q&A

What is Hexapeptide-3 and how does it work?

Hexapeptide-3 is a synthetic biomimetic peptide composed of a specific sequence of amino acids (Ala-Asp-Leu-Lys-Pro-Thr). It mimics a segment of fibronectin, a protein found in the skin's extracellular matrix (ECM) that plays a crucial role in tissue repair, wound healing, and cell adhesion. By replicating these functions, Hexapeptide-3 enhances cell adhesion and the organization of cutaneous tissue, which contributes to a healthier and more youthful appearance of the skin.

What are the primary benefits of using products containing Hexapeptide-3?

Products containing Hexapeptide-3 offer several benefits, primarily related to anti-aging and skin health. These include promoting the production of ECM proteins, enhancing cell adhesion within the dermis, and increasing integrin synthesis, which signals skin repair. As a result, users often experience improved skin smoothness, better hydration, and a noticeable rejuvenation effect.

How does Hexapeptide-3 contribute to anti-aging skincare?

Hexapeptide-3 contributes to anti-aging skincare by promoting the synthesis of extracellular matrix proteins, which are essential for maintaining skin structure and elasticity. Additionally, it strengthens the adhesion between dermal cells, thereby improving the skin's overall texture and firmness. This results in a diminished appearance of wrinkles and a more youthful complexion.

Can Hexapeptide-3 be used for lip care?

Yes, Hexapeptide-3 is frequently incorporated into high-end lip-care products due to its excellent plumping and rejuvenating effects. It improves lip hydration and smoothness, making lips appear fuller and more youthful.

What kind of skin type is best suited for Hexapeptide-3?

Hexapeptide-3 is suitable for all skin types, particularly those in need of anti-aging treatments or enhanced hydration. Individuals looking to improve skin texture and appearance, as well as lip fullness and health, may benefit significantly from products containing Hexapeptide-3.

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