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| Catalog Number | CI-BP-0201 |
| Product Name | Dipeptide-2 |
| CAS | 24587-37-9 |
| Structure |  |
| Synonyms | H-VAL-TRP-OH |
| IUPAC Name | (2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-(1H-indol-3-yl)propanoic acid |
| Molecular Weight | 303.36 g/mol |
| Molecular Formula | C16H21N3O3 |
| InChI | InChI=1S/C16H21N3O3/c1-9(2)14(17)15(20)19-13(16(21)22)7-10-8-18-12-6-4-3-5-11(10)12/h3-6,8-9,13-14,18H,7,17H2,1-2H3,(H,19,20)(H,21,22)/t13-,14-/m0/s1 |
| InChI Key | LZDNBBYBDGBADK-KBPBESRZSA-N |
| Boiling Point | 604.8±55.0 °C |
| Density | 1.268 g/mL |
| Appearance | White powder |
| Storage | -15~-20 °C |
| Isomeric SMILES | CC(C)[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)N |
| pKa | 3.14±0.10 |
| Safety | No heavy metals, no skin and eye irritation |
Dipeptide-2, a bioactive peptide with the sequence Val-Trp (VW), is recognized for its ability to inhibit Angiotensin Converting Enzymes (ACE I and II), thus playing a key role in the regulation of fluid volume within the body. This property makes it particularly valuable in formulations designed to facilitate liquid drainage and enhance circulation. Known for its safety and efficacy, Dipeptide-2 is instrumental in reducing edema, eye bags, and puffiness by promoting increased lymphatic and blood flow. Its decongestant effects are highly sought after in advanced eye care products. Furthermore, Dipeptide-2 is often used synergistically with other peptides, contributing to renowned peptide-based complexes such as Eyeliss™, which is incorporated into many bestselling products.
What is Dipeptide-2 and how does it work?
Dipeptide-2 is a biologically active peptide composed of the amino acid sequence Val-Trp (VW). It functions by inhibiting Angiotensin Converting Enzymes (ACE I and II), which play a key role in regulating the body's fluid volume. This makes it particularly effective in enhancing circulation and promoting liquid drainage, thus reducing edema, eye bags, and puffiness.
What are the main benefits of using Dipeptide-2 in skincare products?
The primary benefits of Dipeptide-2 in skincare include its ability to increase lymphatic and blood circulation, leading to a decongestant effect. This is especially valuable for reducing puffiness and swelling around the eyes. Due to these properties, Dipeptide-2 is commonly used in advanced eye care applications to eliminate unwanted fluid build-up and improve skin appearance.
Is Dipeptide-2 safe for use in skincare formulations?
Yes, Dipeptide-2 is considered a safe ingredient for use in skincare products. Its effectiveness in managing fluid retention and improving circulation makes it a sought-after component in popular peptide-based complexes, which are featured in many bestselling skincare products.
In what types of products is Dipeptide-2 commonly found?
Dipeptide-2 is frequently used in products targeting eye care due to its ability to reduce puffiness and improve circulation. You can typically find it in eye creams, serums, and formulations designed to minimize under-eye bags and other signs of fluid retention in the skin.
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