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| Catalog Number | CI-BP-0161 |
| Product Name | Copper Tripeptide-34 (AHK-Cu) |
| Synonyms | AHK-Cu, L-alanyl-L-histidyl-L-lysine-Cu2+, Copper AHK |
| Molecular Weight | 417.96 g/mol |
| Molecular Formula | C15H26N6O4.Cu2+ |
| Boiling Point | Reduce facical redness and itch/pain on sensitive skin |
| Purity | 95% by HPLC |
| Appearance | Blue powder |
| Application | This product is suitable for shampoo and conditioner. |
| Storage | Keep in dark and cool dry place -5~8°C |
Pyo, Hyun Keol, et al. Archives of pharmacal research, 2007, 30, 834-839.
The tripeptide-copper complex functions as a growth factor that increases dermal fibroblast proliferation along with vascular endothelial growth factor production while decreasing transforming growth factor-β1 secretion by dermal fibroblasts. The research investigated how L-alanyl-L-histidyl-1L-lysine-Cu2+ (AHK-Cu) influences hair growth while examining its mechanism of action through its effects on both proliferation and apoptosis in dermal papilla cells (DPCs).
Key Findings
AHK-Cu (10-12 ~ 10-9 M) caused human hair follicles to elongate in vivo while increasing DPC proliferation in vitro. The flow cytometric analysis using Annexin V-fluorescein isothiocyanate/propidium iodide labeling demonstrated that 10-9M AHK-Cu treatment resulted in fewer apoptotic DPCs although the reduction was not statistically significant. Treatment with 10-9M AHK-Cu raised the Bcl-2/Bax ratio and lowered cleaved caspase-3 and PARP levels. This investigation posits AHK-Cu enhances human hair follicle growth by stimulating DPC proliferation while preventing DPC apoptosis.
What are the primary benefits of Copper Tripeptide-34 for the skin?
Copper Tripeptide-34 is renowned for promoting collagen production, enhancing skin healing, and providing anti-inflammatory benefits. It significantly improves skin elasticity and reduces the appearance of fine lines and wrinkles, contributing to overall skin rejuvenation.
Can Copper Tripeptide-34 be used for hair health?
Yes, Copper Tripeptide-34 is beneficial for hair health. It helps strengthen hair follicles, improve scalp conditions, and promote hair health by balancing the hair life cycle. It achieves this by promoting the proliferation of hair papilla cells, reducing cell apoptosis, and supporting hair follicle elongation.
What ingredients pair well with Copper Tripeptide-34 for optimal skincare results?
For optimal results, pair Copper Tripeptide-34 with other peptides, hyaluronic acid, and antioxidant serums. These combinations can enhance its efficacy in rejuvenating the skin and improving elasticity.
When is the best time to incorporate Copper Tripeptide-34 into my skincare routine?
It is recommended to use Copper Tripeptide-34 during your evening skincare routine. This allows the peptide to work in tandem with your skin's natural repair processes that occur overnight.
How does Copper Tripeptide-34 improve hair quality and scalp condition?
Copper Tripeptide-34 improves hair quality by strengthening hair follicles and promoting hair papilla cell proliferation. It also encourages hair follicle elongation and helps reduce cell apoptosis, leading to improved scalp conditions and healthier hair overall.
If you have any questions, please contact us. You will get a satisfactory answer.
