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Catalog Number | CI-FC-0033 |
Product Name | Carboxymethyl chitosan |
CAS | 83512-85-0 |
Structure | |
Synonyms | N-Carboxymethylchitosan |
IUPAC Name | N-[(2S,3R,4R,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide |
Molecular Weight | 543.52 g/mol |
Molecular Formula | C20H37N3O14 |
InChI | InChI=1S/C20H37N3O14/c1-5(27)23-11-15(31)17(36-19-10(22)13(29)12(28)6(2-24)34-19)8(4-26)35-20(11)37-16-7(3-25)33-18(32)9(21)14(16)30/h6-20,24-26,28-32H,2-4,21-22H2,1H3,(H,23,27)/t6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16?,17?,18-,19+,20+/m1/s1 |
InChI Key | HGNQXZLWHDQLRE-XADFZESNSA-N |
Melting Point | 600 °C |
Appearance | Off-white to pale beige solid |
Isomeric SMILES | CC(=O)N[C@@H]1[C@H](C([C@H](O[C@H]1OC2[C@H](O[C@H]([C@@H]([C@H]2O)N)O)CO)CO)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)N)O |
Carboxymethyl chitosan, a water-soluble derivative of chitosan sourced from natural chitin, is utilized extensively in both personal and oral care products due to its multifaceted properties. In personal care, it serves as a film-forming agent and moisturizer, offering skin protection and a softening effect. Its hyaluronic acid-like characteristics make it ideal for applications in skin, scalp, and hair care, where it forms a protective barrier to prevent moisture loss. Furthermore, in oral care formulations, Carboxymethyl chitosan functions as an anti-plaque component in toothpastes and mouthwashes, effectively combating a wide array of microbes, such as Candida albicans and Staphylococcus aureus. This ingredient is recognized for being safe, non-toxic, and hypoallergenic, ensuring it does not irritate or sensitize the skin, even in sensitive areas.
What is Carboxymethyl Chitosan and how is it derived?
Carboxymethyl Chitosan is a water-soluble derivative of chitosan obtained from natural chitin. It is characterized by its clear to light yellow, slightly viscous liquid form with a distinctive odor.
What are the primary applications of Carboxymethyl Chitosan in personal care products?
In personal care applications, Carboxymethyl Chitosan functions as a film-forming agent, moisturizer, and skin-protecting ingredient. It is also known for its softening properties, making it an ideal component for a variety of skincare preparations.
How does Carboxymethyl Chitosan contribute to oral care products?
Carboxymethyl Chitosan serves as an anti-plaque agent in oral care products such as toothpaste and mouthwash. It is effective against a wide range of microbes common in the oral cavity, including Candida albicans, Staphylococcus aureus, and Streptococcus.
In what ways does Carboxymethyl Chitosan resemble hyaluronic acid in its function?
Carboxymethyl Chitosan shares similar properties with hyaluronic acid, particularly in forming a protective film that prevents transdermal moisture loss. This makes it a valuable ingredient in skin, scalp, and hair care products.
Is Carboxymethyl Chitosan safe for use in cosmetic and personal care products?
Yes, Carboxymethyl Chitosan is a safe ingredient. It is non-toxic, non-irritant, including in eye care applications, and non-sensitizing, making it hypoallergenic and suitable for sensitive skin.
Can Carboxymethyl Chitosan be used in formulations for sensitive skin?
Absolutely, Carboxymethyl Chitosan is non-sensitizing and hypoallergenic, making it appropriate for formulations designed for sensitive skin, as it minimizes the risk of irritation and allergic reactions.