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| Catalog Number | CI-GU-0095 |
| Product Name | Caprylhydroxamic Acid |
| CAS | 7377-03-9 |
| Structure |  |
| Synonyms | n-Hydroxy-octanamid |
| IUPAC Name | N-hydroxyoctanamide |
| Molecular Weight | 159.23 g/mol |
| Molecular Formula | C8H17NO2 |
| InChI | InChI=1S/C8H17NO2/c1-2-3-4-5-6-7-8(10)9-11/h11H,2-7H2,1H3,(H,9,10) |
| InChI Key | RGUVUPQQFXCJFC-UHFFFAOYSA-N |
| Melting Point | 78 °C |
| Purity | 95% |
| Density | 0.97 g/mL |
| Appearance | Solid |
| Highest Usage In Residency Products | 0.0012 |
| Isomeric SMILES | CCCCCCCC(=O)NO |
| pKa | 9.56±0.20 |
Caprylhydroxamic Acid (CHA) is utilized in personal care products primarily for its preservative and chelating properties. It effectively inhibits the growth of bacteria, yeast, and mold within a pH range of 4 to 7.5, making it particularly suitable for skincare applications. CHA is soluble in solvents like glycols and glycerin, allowing for seamless incorporation into various formulations, including anhydrous systems, creams, and lotions. It demonstrates compatibility with a broad spectrum of personal care ingredients; however, it may form colored complexes with certain mineral smectite clays containing iron. Additionally, due to its hydroxamic nature, Caprylhydroxamic Acid acts as a chelating agent, binding with metal ions such as iron and lead, thus safeguarding the product and skin from potential heavy metal contamination.
What is Caprylhydroxamic Acid, and what are its primary applications in personal care products?
Caprylhydroxamic Acid (CHA) is a hydroxamic acid used primarily in personal care formulations as a preservative and a chelating agent. It effectively suppresses microbial growth, acting against bacteria, yeast, and mold in the pH range of 4 to 7.5, which is ideal for skincare products. Additionally, it forms complexes with metal ions, providing protection against heavy metal contamination in both the product and the skin.
How does Caprylhydroxamic Acid function as a preservative?
As a preservative, Caprylhydroxamic Acid works by inhibiting the growth of bacteria, yeast, and mold within the slightly acidic to neutral pH range of 4 to 7.5. This feature makes it particularly suitable for skincare applications, where maintaining an appropriate preservative system is critical to ensure product safety and efficacy.
Can Caprylhydroxamic Acid be used in all types of personal care formulations?
Yes, Caprylhydroxamic Acid can be incorporated into almost all personal care formulations. It is soluble in glycols and glycerin and can be utilized in anhydrous systems, creams, and lotions. However, it is important to be cautious when using it with certain mineral smectite clays containing iron ions, as it can form slightly orange to red-colored complexes with these materials.
What is the significance of Caprylhydroxamic Acid's chelating properties?
Caprylhydroxamic Acid's ability to act as a chelating agent is significant because it helps in forming complexes with metal ions such as iron and lead. This ability not only aids in stabilizing the formulation by preventing metal-induced degradation but also protects the skin from potential harmful effects of heavy metal contamination.
Are there any specific compatibility concerns when using Caprylhydroxamic Acid in formulations?
While Caprylhydroxamic Acid is compatible with a wide range of ingredients commonly used in personal care products, it can react with some mineral smectite clays that contain iron ions. This reaction may result in slightly orange to red-colored complexes, so formulators should take this into account when designing products with these clays.
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