Our customer service representatives are available 24 hours a day, from Monday to Sunday.

Caprooyl tetrapeptide-3

Online Inquiry

Catalog Number	CI-BP-0069
Product Name	Caprooyl tetrapeptide-3
CAS	1012317-71-3
Structure
Synonyms	N2-(1-Oxohexyl)-L-lysylglycyl-L-histidyl-L-lysinamide acetate
IUPAC Name	acetic acid;(2S)-6-amino-2-[[(2S)-2-[[2-[[(2S)-6-amino-2-(hexanoylamino)hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanamide
Molecular Weight	625.77 g/mol
Molecular Formula	C28H51N9O7
InChI	InChI=1S/C26H47N9O5.C2H4O2/c1-2-3-4-11-22(36)33-20(10-6-8-13-28)25(39)31-16-23(37)34-21(14-18-15-30-17-32-18)26(40)35-19(24(29)38)9-5-7-12-27;1-2(3)4/h15,17,19-21H,2-14,16,27-28H2,1H3,(H2,29,38)(H,30,32)(H,31,39)(H,33,36)(H,34,37)(H,35,40);1H3,(H,3,4)/t19-,20-,21-;/m0./s1
InChI Key	UAAVFMYNDSZDNL-OCIDDWSYSA-N
Purity	0.95
Appearance	White powder
Storage	-15~-20 °C
Isomeric SMILES	CCCCCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)N.CC(=O)O
Safety	No heavy metals, no skin and eye irritation

Product Overview

Caprooyl tetrapeptide-3, also known as KGHK-Caproic acid, is a biomimetic lipid structure that mimics the functions of transforming growth factor beta (TGF-ß) to support the natural synthesis of the extracellular matrix in the skin. Its peptide sequence, Lys-Gly-His-Lys, effectively minimizes the visibility of fine lines and wrinkles, enhances skin elasticity, and combats stretch marks. Scientific research indicates that Caprooyl tetrapeptide-3 can significantly increase the production of dermal-epidermal junction (DEJ) structural proteins, such as laminin and fibronectin, by up to 26% and 60% respectively, thereby improving the skin's mechanical properties. Moreover, studies in skin aging models have shown that this peptide enhances gene expression for collagen VII and laminin-5, which are crucial for reinforcing the connection between the epidermis and dermis at the DEJ. In clinical trials involving ChroNOline™, an active formulation containing Caprooyl tetrapeptide-3, participants noted a noticeable reduction in fine lines and wrinkles, with improvements of up to 27%. The trial involved 27 female volunteers aged 40 to 65, who also reported enhanced skin smoothness, firmness, and a more youthful appearance.

Custom Q&A

What is Caprooyl tetrapeptide-3 and how does it work?

Caprooyl tetrapeptide-3, also known as KGHK-Caproic acid, is a biomimetic lipopeptide designed to mimic the function of the transforming growth factor beta (TGF-ß). This peptide is essential in promoting the natural production of extracellular matrix components. It primarily works by decreasing the appearance of fine lines and wrinkles, enhancing skin elasticity, and combating stretch marks.

How does Caprooyl tetrapeptide-3 improve skin structure?

Caprooyl tetrapeptide-3 boosts the production of structural proteins at the dermal-epidermal junction (DEJ), such as laminin and fibronectin. Research indicates that laminin production can increase by up to 26% and fibronectin by up to 60%, significantly improving the mechanical properties of the skin. Additionally, it enhances the expression of genes responsible for the production of collagen VII and laminin-5, which are crucial for strengthening the adhesion of the epidermis to the dermis at the DEJ.

What are the observed benefits of using Caprooyl tetrapeptide-3 in skincare products?

Clinical studies have demonstrated that skincare formulations containing Caprooyl tetrapeptide-3 can significantly reduce the appearance of fine lines and wrinkles by up to 27%. Users have reported noticeable anti-aging effects, including increased skin smoothness, firmness, and an overall younger-looking appearance.

Who participated in the clinical study on Caprooyl tetrapeptide-3, and what were the results?

The clinical study involved 27 female volunteers aged between 40 and 65. These participants used a face cream based on Caprooyl tetrapeptide-3. The study showed a significant decrease in the appearance of fine lines and wrinkles, along with spontaneous reports of enhanced skin smoothness, firmness, and a more youthful appearance.

Online Inquiry