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Catalog Number | CI-SC-1272 |
Product Name | Asiatic Acid |
CAS | 464-92-6 |
Structure | |
Synonyms | (4R)-2α,3β,23-Trihydroxyurs-12-en-28-oic acid |
IUPAC Name | (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid |
Molecular Weight | 488.7 g/mol |
Molecular Formula | C30H48O5 |
InChI | InChI=1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21-,22-,23+,24+,26+,27+,28-,29-,30+/m1/s1 |
InChI Key | JXSVIVRDWWRQRT-UYDOISQJSA-N |
Boiling Point | 609.4±55.0 °C |
Melting Point | 325-330 °C |
Purity | 95% |
Density | 1.18 g/mL |
Appearance | Solid |
Highest Usage In Residency Products | 0.003 |
Isomeric SMILES | C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(C[C@H]([C@@H]([C@@]5(C)CO)O)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O |
Asiatic acid, a polyhydroxy acid with a pentacyclic triterpene structure, is renowned for its beneficial properties initially extracted from the medicinal plant Gotu Kola. It offers notable healing, protective, and anti-inflammatory effects on the skin. This natural antioxidant, prevalent in plants like glossy privet fruit, basil, and brown mustard, has been extensively studied for its therapeutic potential. Asiatic acid is celebrated for its wound-healing, anti-aging, and anti-fungal properties, making it an ideal component in skincare products. It effectively mitigates UV-induced inflammation and neutralizes harmful free radicals, including reactive oxygen species, nitric oxide, and protein carbonyl groups. Furthermore, it safeguards collagen and elastin fibers from glycation, maintaining skin elasticity, firmness, and youthfulness. This polyhydroxy acid also promotes the production of collagen types I and III, imparting a significant anti-aging impact. By reducing inflammatory cytokines, Asiatic acid functions as both an immunomodulatory and anti-inflammatory agent, soothing irritated skin and proving effective against conditions such as atopic dermatitis. Thus, derived from traditional medicine, Asiatic acid has emerged as a prominent ingredient in contemporary premium skincare formulations.
What are the primary benefits of Asiatic Acid for the skin?
Asiatic Acid, derived from the Gotu Kola plant, offers various benefits for the skin, including wound healing, anti-aging, and anti-fungal properties. It acts as a powerful antioxidant, soothing UV-induced inflammation and scavenging free radicals. Furthermore, it protects collagen and elastin fibers from glycation and stimulates the production of collagen type I and III, contributing to improved skin elasticity and firmness. It is also effective in reducing inflammatory cytokines, making it suitable for treating conditions such as atopic dermatitis.
How does Asiatic Acid contribute to anti-aging skincare formulations?
Asiatic Acid is highly regarded for its anti-aging effects due to its ability to stimulate collagen production, specifically type I and III. By promoting collagen synthesis, it helps maintain skin elasticity and firmness, reducing the appearance of fine lines and wrinkles. Additionally, Asiatic Acid protects collagen and elastin fibers from glycation, which is a process that can accelerate aging, thereby preserving the skin's youthful appearance.
Can Asiatic Acid be used for treating skin conditions like atopic dermatitis?
Yes, Asiatic Acid is effective in managing skin conditions such as atopic dermatitis. It acts as an immunomodulatory and anti-inflammatory agent, helping to soothe irritated skin. By reducing inflammatory cytokines, Asiatic Acid can alleviate symptoms associated with inflammatory skin conditions, making it a beneficial component in treatment regimens for atopic dermatitis.
What makes Asiatic Acid a preferred ingredient in modern high-end skincare formulas?
Asiatic Acid has become a favored ingredient in modern high-end skincare formulations due to its comprehensive skin benefits rooted in traditional medicine. Its antioxidant properties provide protection against environmental stressors, while its anti-inflammatory effects soothe and calm the skin. Additionally, its capacity to enhance collagen synthesis and maintain skin elasticity positions it as a vital ingredient in achieving a youthful and healthy complexion.
Is Asiatic Acid suitable for all skin types, including sensitive skin?
Asiatic Acid is generally suitable for all skin types, including sensitive skin. Its anti-inflammatory and soothing properties make it especially beneficial for individuals with sensitive or irritated skin. However, as with any skincare product, it is advisable to perform a patch test prior to full application, particularly if you have extremely sensitive skin or known allergies.