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| Catalog Number | CI-SC-0560 |
| Product Name | Ascorbyl Glucoside |
| CAS | 129499-78-1 |
| Structure |  |
| Synonyms | Ascorbic acid 2-O-glucoside;2-O-alpha-D-Glucopyranosyl-L-ascorbic acid;L-Ascorbic acid 2-O-alpha-glucoside |
| Description | Ascorbyl glucoside is a form of vitamin C that is used in skincare and cosmetic products. It is a water-soluble derivative of vitamin C that is more stable and less irritating than pure vitamin C. It is a potent antioxidant that protects the skin from damaging free radicals and helps to brighten the complexion by inhibiting melanin production. Ascorbyl glucoside also promotes collagen synthesis, which can help to improve the texture and elasticity of the skin, and has anti-inflammatory properties that can help to soothe and calm irritated skin. Overall, ascorbyl glucoside is a popular ingredient in anti-aging, brightening, and protective skincare products. |
| Molecular Weight | 338.26 g/mol |
| Molecular Formula | C12H18O11 |
| Flash Point | 271.8°C |
| Density | 1.83 g/mL |
| Appearance | white to off-white powder or crystalline powder |
| Application | 1. Ascorbyl Glucoside is a stable form of Vitamin C that is used in skincare products. 2. It helps in brightening the skin and reducing dark spots and hyperpigmentation. 3. It is known for its antioxidant properties that protect the skin from harmful free radicals. 4. Ascorbyl Glucoside also helps in collagen synthesis, which improves skin elasticity and reduces fine lines and wrinkles. 5. It is suitable for all skin types and can be used in various skincare products like serums, creams, and lotions. |
| Features And Benefits | 1. Brightens skin tone 2. Reduces dark spots and hyperpigmentation 3. Acts as an antioxidant to protect against free radical damage 4. Boosts collagen production 5. Improves skin texture and elasticity 6. Provides anti-aging benefits 7. Reduces inflammation and redness 8. Compatible with other skincare ingredients. |
| Refractive Index | 1.67 |
Hakozaki, Tomohiro, et al. Skin Research and Technology, 2006, 12(2), 105-113.
This work demonstrated that the use of high-frequency ultrasound and coupling gel containing skin whitening agents can effectively improve facial pigmentation by enhancing the transepidermal transport of the whitening agents. The whitening gel sample was a coupling gel containing 2% ascorbyl glucoside and 3.5% niacinamide as whitening active agents.
Experimental methods and results
· The impact of ultrasound on the absorption of skin-lightening agents into the stratum corneum was examined using a tape-stripping method on human forearms in vivo. A facial clinical trial involving 60 participants with hyperpigmentation was conducted in a paired design to evaluate the efficacy of the skin treatments.
· The participants were split into two groups, with each group receiving two different treatments on each facial cheek: skin-lightening gel with ultrasound versus no treatment, and skin-lightening gel with ultrasound versus skin-lightening gel treatment. Changes in facial hyperpigmentation were measured through computer analysis and visual grading of high-resolution digital images of the face, as well as through a subjective questionnaire.
· The results showed that ultrasound radiation increased the absorption of skin-lightening agents in the stratum corneum in a time-dependent manner. In the facial clinical trial, the combination of ultrasound radiation and skin-lightening gel led to a significant reduction in facial hyperpigmented spots compared to both no treatment and using the skin-lightening gel alone after 4 weeks.
What is ascorbyl glucoside?
Ascorbyl glucoside is a stable form of vitamin C combined with the sugar glucose.
How is ascorbyl glucoside absorbed into the skin?
When properly formulated and absorbed into the skin, ascorbyl glucoside breaks down to ascorbic acid, also known as pure vitamin C.
What is the reservoir effect of ascorbyl glucoside?
Ascorbyl glucoside creates a reservoir effect within the skin, leading to longer-lasting benefits.
How does ascorbyl glucoside improve skin tone and hyperpigmentation?
Ascorbyl glucoside inhibits the production of pigment and can be useful in treating hyperpigmentation, uneven skin tones, and age spots.
What other ingredient works well with ascorbyl glucoside?
Ascorbyl glucoside works well with niacinamide, a type of vitamin B, to address issues such as loss of firmness and elasticity, wrinkles and fine lines, unevenness in the complexion, and large pores.
What concentration of ascorbyl glucoside is typically used for brightening dull skin?
Ascorbyl glucoside is typically used in concentrations of 2-5% for brightening dull skin and fading hyperpigmentation.
Is ascorbyl glucoside safe to use in cosmetics?
Ascorbyl glucoside is considered safe for use in cosmetics, both rinse-off and leave-on.
What is the pH range at which ascorbyl glucoside works best?
Ascorbyl glucoside works between a pH of 5-8, with the lower end of the spectrum considered better due to being a close match to the normal pH range of skin.
What are the main benefits of ascorbyl glucoside for skin?
Ascorbyl glucoside neutralizes skin-damaging free radicals, inhibits the production of pigment to fade and prevent dark spots, and boosts collagen production.
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