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| Catalog Number | CI-SC-1300 |
| Product Name | Adenine |
| CAS | 73-24-5 |
| Structure |  |
| Synonyms | Purine, 6-amino-;9H-Purin-6-amine |
| IUPAC Name | 7H-purin-6-amine |
| Molecular Weight | 135.13 g/mol |
| Molecular Formula | C5H5N5 |
| InChI | InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10) |
| InChI Key | GFFGJBXGBJISGV-UHFFFAOYSA-N |
| Purity | 95% |
| Density | 1.38 g/mL |
| Appearance | Liquid or Solid |
| Highest Usage In Residency Products | 0.0125 |
| Isomeric SMILES | C1=NC2=NC=NC(=C2N1)N |
| pKa | 4.12 |
Adenine, a key purine nucleobase found in both plant and human DNA, serves as a critical cellular self-repair factor. It plays an essential role in repairing DNA damage caused by UVA and UVB radiation, thereby enabling cells to maintain their vital functions. Additionally, adenine exhibits strong antioxidant properties by stimulating the superoxide dismutase enzyme, which, in conjunction with endogenous copper ions, effectively neutralizes free radicals. Moreover, it stimulates rRNA and tRNA activity, thereby enhancing protein metabolism and contributing to the stabilization and normalization of collagen and elastin synthesis by fibroblasts.
What are the primary functions of Adenine in cellular repair?
Adenine plays a critical role in cellular self-repair through three primary mechanisms. Firstly, it repairs DNA that has been damaged by UVA/UVB radiation, thereby allowing the cell to continue its vital processes. Secondly, it exerts a potent antioxidant effect by stimulating the superoxide dismutase enzyme, which, in combination with endogenous copper ions, directly neutralizes free radicals. Lastly, Adenine stimulates rRNA and tRNA, enhancing protein metabolism and stabilizing collagen and elastin synthesis by fibroblasts.
How does Adenine contribute to antioxidant activity in cells?
Adenine enhances antioxidant activity by stimulating the superoxide dismutase enzyme. This enzyme, when paired with endogenous copper ions, directly neutralizes free radicals. This action helps protect cells from oxidative stress, which can lead to cellular damage and aging.
In what way does Adenine influence protein metabolism?
Adenine influences protein metabolism by stimulating rRNA and tRNA. This stimulation enhances the synthesis of proteins, which stabilizes and normalizes the production of collagen and elastin by fibroblasts. These proteins are essential for maintaining the structural integrity and elasticity of tissues.
Can Adenine be beneficial for skin exposed to sunlight?
Yes, Adenine can be beneficial for skin exposed to sunlight. It repairs DNA that has been damaged by UVA/UVB radiation, which helps to maintain cellular health and function, protecting the skin from the harmful effects of sun exposure.
Is Adenine naturally occurring in the human body?
Yes, Adenine is a naturally occurring substance found in both plants and humans. It is one of the four purine nucleobases in DNA and plays a vital role in cellular functions and repair mechanisms within the body.
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