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Acetyl tetrapeptide-2

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Catalog Number	CI-BP-0010
Product Name	Acetyl tetrapeptide-2
CAS	1239011-60-9
Synonyms	N2-Acetyl-D-lysyl-L-alpha-aspartyl-L-valyl-3-hydroxyphenylalaninamide
IUPAC Name	(3S)-3-[[(2R)-2-acetamido-6-aminohexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-amino-3-(3-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Molecular Weight	564.63 g/mol
Molecular Formula	C26H40N6O8
InChI	InChI=1S/C26H40N6O8/c1-14(2)22(26(40)30-19(23(28)37)12-16-7-6-8-17(34)11-16)32-25(39)20(13-21(35)36)31-24(38)18(29-15(3)33)9-4-5-10-27/h6-8,11,14,18-20,22,34H,4-5,9-10,12-13,27H2,1-3H3,(H2,28,37)(H,29,33)(H,30,40)(H,31,38)(H,32,39)(H,35,36)/t18-,19+,20+,22+/m1/s1
InChI Key	DILGXAPUHJNKLH-AQCRLBJHSA-N
Application	It can be used to stimulate the skin immune defenses and to help the skin regenerate.
Isomeric SMILES	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC(=CC=C1)O)C(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](CCCCN)NC(=O)C

Product Overview

Acetyl Tetrapeptide-2, a synthetic compound also recognized by the trade name Peptigravity, plays a crucial role in addressing skin sagging by enhancing the skin's intrinsic protein structures such as collagen and elastin. This peptide stimulates critical skin components, thereby improving the cohesion between skin cells and the extracellular matrix (ECM). By activating key glycoproteins like FBLN5 and LOXL1, it ensures the proper organization and functionality of elastin fibers, contributing to the skin's firmness and resilience. This action helps maintain facial contours and mitigate the effects of gravity by increasing the expression of collagen and elastin genes and reorganizing their fiber structures. Acetyl Tetrapeptide-2 is commonly utilized in anti-aging skincare formulations to support the facial structure and reduce sagging in areas such as the chest and neck. Furthermore, it is incorporated in premium products designed for individuals who have experienced significant weight loss, aiding in the redefinition and cohesion of the dermal layer.

Custom Q&A

What is Acetyl Tetrapeptide-2 and how does it work?

Acetyl Tetrapeptide-2 is a synthetic peptide with the sequence Ac-Lys-Asp-Val-Tyr. It is designed to combat skin sagging by stimulating the skin's essential proteins, such as collagen and elastin. This peptide enhances cell cohesion and the extracellular matrix, supporting skin firmness and resistance.

What are the key benefits of using Acetyl Tetrapeptide-2 in skincare?

Acetyl Tetrapeptide-2 offers several benefits, including lifting the skin, maintaining facial contour, and preventing skin sagging. It activates glycoproteins like FBLN5 and LOXL1, vital for organizing and maintaining elastin fibers, which improves the overall elasticity and firmness of the skin.

How does Acetyl Tetrapeptide-2 enhance collagen and elastin production?

The peptide increases the expression of collagen and elastin genes, thereby helping to prevent gravitational effects. It plays a critical role in reorganizing these fibers, promoting their cohesion with the extracellular matrix and improving dermal structure and communication.

What types of skincare products contain Acetyl Tetrapeptide-2?

Acetyl Tetrapeptide-2 is commonly found in anti-aging products designed to maintain facial contour and reduce sagging in areas such as the chest and neck. It is also utilized in premium formulations for post-weight-loss skin care products.

Is Acetyl Tetrapeptide-2 safe for all skin types?

While Acetyl Tetrapeptide-2 is generally safe for most skin types, it is always advisable to perform a patch test before incorporating a new product into your skincare routine. Consult with a dermatologist for personalized advice, especially if you have sensitive or reactive skin.

Does Acetyl Tetrapeptide-2 have any side effects?

Acetyl Tetrapeptide-2 is typically well-tolerated, but as with any skincare ingredient, individual reactions can vary. There might be rare cases of irritation or allergic reactions, so it's important to monitor how your skin responds to products containing this peptide.

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