Our customer service representatives are available 24 hours a day, from Monday to Sunday.
| Catalog Number | CI-BP-0146 |
| Product Name | Acetyl dipeptide-1 cetyl ester |
| CAS | 196604-48-5 |
| Structure |  |
| Synonyms | Ac-Tyr-Arg-O-hexadecyl ester,Acetyl Dipeptide-1 Cetyl Ester |
| IUPAC Name | hexadecyl (2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoate |
| Molecular Weight | 603.84 g/mol |
| Molecular Formula | C33H57N5O5 |
| InChI | InChI=1S/C33H57N5O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-24-43-32(42)29(18-17-23-36-33(34)35)38-31(41)30(37-26(2)39)25-27-19-21-28(40)22-20-27/h19-22,29-30,40H,3-18,23-25H2,1-2H3,(H,37,39)(H,38,41)(H4,34,35,36)/t29-,30-/m0/s1 |
| InChI Key | JFHZXDZUXGBFAQ-KYJUHHDHSA-N |
| Purity | 0.95 |
| Density | 1.12 g/mL |
| Appearance | White powder |
| Storage | -15~-20 °C |
| Isomeric SMILES | CCCCCCCCCCCCCCCCOC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C |
| pKa | 9.83±0.15 |
| Safety | No heavy metals, no skin and eye irritation |
Acetyl Dipeptide-1 Cetyl Ester, commercially known as Idealift™, is a cutting-edge lipopeptide developed by Sederma that is specifically formulated to enhance elastin production, thereby addressing skin sagging and the effects of gravity on the skin. This innovative ingredient is highly effective in combating the appearance of aging-related skin laxity and daily environmental aggressors. In vitro studies have demonstrated its ability to significantly boost elastin synthesis and improve the architecture of elastin fibers, with a noted increase in elastin/tropoelastin within the extracellular matrix by over 94%. Idealift™ also plays a crucial role in the comprehensive process of elastic tissue formation and maturation, assisting in the stabilization and anchoring of elastin alongside proteins such as Fibrillin-1, Fibulin-5, and the enzyme Lysyl Oxidase. Clinical trials involving female volunteers aged 54 to 75, who applied a 4% concentration of Acetyl Dipeptide-1 Cetyl Ester over two months, underscored its efficacy. Results were validated through a variety of advanced evaluation methodologies, leading to a noticeable improvement in skin firmness and a reduction in the effects of gravitational pull. With 80% of participants observing firmer skin, Acetyl Dipeptide-1 Cetyl Ester stands out as an essential component in formulations designed to combat skin sagging and enhance overall skin resilience.
What is Acetyl Dipeptide-1 Cetyl Ester, and how does it work?
Acetyl Dipeptide-1 Cetyl Ester, an active lipopeptide, is designed to combat cutaneous sagging and reduce the visible effects of gravity on the skin, particularly targeting areas prone to flaccidity, like jowls, due to aging or environmental stressors. This lipopeptide works by stimulating elastin production, which helps maintain the skin's elasticity and firmness, making it an ideal ingredient for anti-aging formulations.
What are the scientific findings on the efficacy of Acetyl Dipeptide-1 Cetyl Ester?
The efficacy of Acetyl Dipeptide-1 Cetyl Ester has been demonstrated through in vitro studies, which show a significant increase in elastin synthesis and improved elastin fiber architecture. The quantity of elastin/tropoelastin in the extracellular matrix increased by more than 94% following fibroblast release, indicating strong potential in enhancing skin elasticity. Furthermore, the ingredient aids in the stages of elastic tissue formation and maturation, which are essential for maintaining robust skin structure and function.
How was Acetyl Dipeptide-1 Cetyl Ester tested in human studies?
Acetyl Dipeptide-1 Cetyl Ester was tested in a clinical study involving 26 female volunteers aged 54 to 75 who experienced sagging skin. Participants applied a cream containing 4% of the lipopeptide twice daily for two months. The study results were impressive; after just one month, significant improvements in skin firmness and reductions in sagging were observed in 80% of the panelists.
What benefits does Acetyl Dipeptide-1 Cetyl Ester offer in skincare formulations?
Acetyl Dipeptide-1 Cetyl Ester provides multiple benefits in skincare products, primarily focusing on anti-aging effects. It helps fight skin sagging, increases resistance to gravitational effects, and enhances firmness, contributing to a more youthful appearance. This ingredient is particularly valuable in formulations targeted at mature skin, aiming to restore resilience and vitality that may diminish with age.
If you have any questions, please contact us. You will get a satisfactory answer.
